Regulation of oxysterol 7A-hydroxylase (CYP7b1) in primary cultures of rat hepatocytes by bile acids (BA), cholesterol (chol), cAMP and phorbol ester.

被引:0
|
作者
Pandak, WM [1 ]
Zhao, LJ [1 ]
Hylemon, PB [1 ]
Vlahcevic, ZR [1 ]
机构
[1] Virginia Commonwealth Univ, Richmond, VA USA
关键词
D O I
10.1016/S0016-5085(00)86140-5
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
1166
引用
收藏
页码:A998 / A998
页数:1
相关论文
共 20 条
  • [1] Regulation of oxysterol 7α-hydroxylase (CYP7B1) in primary cultures of rat hepatocytes
    Pandak, WM
    Hylemon, PB
    Ren, SL
    Marques, D
    Gil, G
    Redford, K
    Mallonee, D
    Vlahcevic, ZR
    HEPATOLOGY, 2002, 35 (06) : 1400 - 1408
  • [2] Regulation of oxysterol 7α-hydroxylase (CYP7B1) in the rat
    Ren, S
    Marques, D
    Redford, K
    Hylemon, PB
    Gil, G
    Vlahcevic, ZR
    Pandak, WM
    METABOLISM-CLINICAL AND EXPERIMENTAL, 2003, 52 (05): : 636 - 642
  • [3] Bile acids and FXR represses cholesterol 7A-hydroxylase (CYP7A1), sterol 12A-hydroxylase (CYP8B1) and sterol 27-hydroxylase (CYP27A1), but not oxysterol 7A-hydroxylase (CYP7B1) gene transcription.
    Chiang, JY
    Chen, W
    Zheng, M
    Wu, Z
    Kimmel, R
    Stroup, D
    GASTROENTEROLOGY, 2000, 118 (04) : A1006 - A1006
  • [4] Transcriptional regulation of human oxysterol 7α-hydroxylase (CYP7B1) by bile acids and nuclear receptors.
    Norlin, M
    Chiang, JY
    HEPATOLOGY, 2002, 36 (04) : 241A - 241A
  • [5] Transcriptional regulation of human oxysterol 7α-hydroxylase gene (CYP7B1) by Sp1
    Wu, ZL
    Chiang, JYL
    GENE, 2001, 272 (1-2) : 191 - 197
  • [6] Human steroid and oxysterol 7a-hydroxylase CYP7B1: substrate specificity, azole binding and misfolding of clinically relevant mutants
    Yantsevich, Aleksei V.
    Dichenko, Yaroslav V.
    MacKenzie, Farrell
    Mukha, Dmitry V.
    Baranovsky, Alexander V.
    Gilep, Andrei A.
    Usanov, Sergey A.
    Strushkevich, Natallia V.
    FEBS JOURNAL, 2014, 281 (06) : 1700 - 1713
  • [7] TRANSCRIPTIONAL REGULATION OF CHOLESTEROL 7-ALPHA-HYDROXYLASE MESSENGER-RNA BY CONJUGATED BILE-ACIDS IN PRIMARY CULTURES OF RAT HEPATOCYTES
    STRAVITZ, RT
    HYLEMON, PB
    HEUMAN, DM
    HAGEY, LR
    SCHTEINGART, CD
    TONNU, HT
    HOFMANN, AF
    VLAHCEVIC, ZR
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1993, 268 (19) : 13987 - 13993
  • [8] Bile acid induced signal transductive pathways involved in regulation of cholesterol 7a-hydroxylase (CYP7A1) transcription.
    Gupta, S
    Stravitz, RT
    Dent, P
    Vlahcevic, ZR
    Hylemon, PB
    GASTROENTEROLOGY, 2000, 118 (04) : A2 - A2
  • [9] Transcriptional regulation of the rat cholesterol 7 alpha-hydroxylase gene (CYP7A) by bile acids.
    Chiang, JYL
    Crestani, M
    Stroup, D
    FASEB JOURNAL, 1996, 10 (06): : 2866 - 2866
  • [10] Glucagon and cAMP inhibit cholesterol 7α-hydroxylase (CYP7A1) gene expression in human hepatocytes:: Discordant regulation of bile acid synthesis and gluconeogenesis
    Song, KH
    Chiang, JYL
    HEPATOLOGY, 2006, 43 (01) : 117 - 125