Carbapenem-resistant Pseudomonas aeruginosa in Malaysia producing IMP-7 β-lactamase

被引：28

作者：

Ho, SE ^{[1
]}

Subramaniam, G ^{[1
]}

Palasubramaniam, S ^{[1
]}

Navaratnam, P ^{[1
]}

机构：

[1] Univ Malaya, Fac Med, Dept Med Microbiol, Kuala Lumpur 50603, Malaysia

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2002年 / 46卷 / 10期

关键词：

D O I：

10.1128/AAC.46.10.3286-3287.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We have isolated and identified a carbapenem-resistant Pseudomonas aeruginosa strain from Malaysia that produces an IMP-7 metallo-beta-lactamase. This isolate showed high-level resistance to meropenem and imipenem, the MICs of which were 256 and 128 mug/ml, respectively. Isoelectric focusing analyses revealed pI values of >9.0, 8.2, and 7.8, which indicated the possible presence of IMP and OXA. DNA sequencing confirmed the identity of the IMP-7 determinant.

引用

页码：3286 / 3287

页数：2

共 13 条

[1]

Arakawa Y, 2000, J CLIN MICROBIOL, V38, P40

[2] IMP-4, a novel metallo-β-lactamase from nosocomial Acinetobacter spp. collected in Hong Kong between 1994 and 1998 [J].

Chu, YW ;

Afzal-Shah, M ;

Houang, ETS ;

Palepou, MFI ;

Lyon, DJ ;

Woodford, N ;

Livermore, DM .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (03) :710-714

[3] Nosocomial outbreak of carbapenem-resistant Pseudomonas aeruginosa with a new blaIMP allele, blaIMP-7 [J].

Gibb, AP ;

Tribuddharat, C ;

Moore, RA ;

Louie, TJ ;

Krulicki, W ;

Livermore, DM ;

Palepou, MFI .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2002, 46 (01) :255-258

[4] RAPID PROCEDURE FOR DETECTION AND ISOLATION OF LARGE AND SMALL PLASMIDS [J].

KADO, CI ;

LIU, ST .

JOURNAL OF BACTERIOLOGY, 1981, 145 (03) :1365-1373

[5]

Köhler T, 1999, J BACTERIOL, V181, P6300

[6] Structure of In31, a blaIMP-containing Pseudomonas aeruginosa integron phyletically related to In5, which carries an unusual array of gene cassettes [J].

Laraki, N ;

Galleni, M ;

Thamm, I ;

Riccio, ML ;

Amicosante, G ;

Frère, JM ;

Rossolini, GM .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (04) :890-901

[7]

*NAT COMM CLIN LAB, 1995, M100A6 NAT COMM CLIN

[8] Outbreak of TEM-24-producing Enterobacter aerogenes in an intensive care unit and dissemination of the extended-spectrum beta-lactamase to other members of the family Enterobacteriaceae [J].

Neuwirth, C ;

Siebor, E ;

Lopez, J ;

Pechinot, A ;

Kazmierczak, A .

JOURNAL OF CLINICAL MICROBIOLOGY, 1996, 34 (01) :76-79

[9]

Sambrook J., 2002, MOL CLONING LAB MANU

[10] PCR detection of metallo-beta-lactamase gene (bla(IMP)) in gram-negative rods resistant to broad-spectrum beta-lactams [J].

Senda, K ;

Arakawa, Y ;

Ichiyama, S ;

Nakashima, K ;

Ito, H ;

Ohsuka, S ;

Shimokata, K ;

Kato, N ;

Ohta, M .

JOURNAL OF CLINICAL MICROBIOLOGY, 1996, 34 (12) :2909-2913

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