Role of Probiotics in Human Health

被引:67
作者
Bodke, Harsh [1 ]
Jogdand, Sangita [1 ]
机构
[1] Jawaharlal Nehru Med Coll, Datta Meghe Inst Med Sci, Pharmacol, Wardha, India
关键词
lactobacilli; immunomodulation; probiotics; intestinal disease; gut microflora; PLACEBO-CONTROLLED TRIAL; MUTANS STREPTOCOCCI; LACTOBACILLUS-RHAMNOSUS; ICE-CREAM; BIFIDOBACTERIUM; DIARRHEA; STRAINS; DISEASE; RECURRENCE; PREVENTION;
D O I
10.7759/cureus.31313
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Certain bacteria, known as probiotics, have had a vastly beneficial effect on people's health; considering their benefits they have been mixed with a wide variety of foods for several decades now. The ability of probiotics to modify the immunological response of the host, antagonize pathogenic microbes, or compete for adhesion sites with pathogenic microorganisms is related to the action of probiotics against microorganisms. Infections of the digestive tract, irritable bowel, lactose intolerance, allergies, infections of the urogenital tract, cystic fibrosis, and various cancers can all be prevented and treated with the use of probiotics. They can reduce the side effects of various antibodies. In the field of oral health, dental caries, periodontal disease, and bad breath can be prevented and treated with the use of probiotics. The findings of several of these clinical studies indicate that probiotics may be beneficial in the treatment and prevention of various diseases and health issues. Validation of a significant number of these clinical investigations is necessary before the results can be applied to the clinical setting. Clinical studies play an important part in such investigations, and in the not-too-distant future, the outcomes of such trials will determine whether or not probiotics are effective in the treatment of disease. This article will attempt to provide a summary of the available literature on the benefits that these probiotics have with regard to health and disease. Probiotics are foods and/or supplements that contain non-pathogenic microbes such as bacteria and yeast that colonize the gut and can potentially yield a variety of health benefits. Research into the various ways in which probiotic bacteria could be used in the treatment of intestinal disorders is ongoing. Thanks to clinical studies and laboratory experiments, we now know more about how probiotics affect gut microbiome disorders. Studies can prove that probiotics can alleviate a variety of gastrointestinal ailments and improve overall health. This article concentrates on probiotics and commensal microbes, as well as their potential role in gut microbiome- related illnesses. In this section, we mark certain areas that need further work and studies so as to enhance our understanding of how probiotics help in the treatment and reduction of chances of gastrointestinal diseases.
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共 53 条
[1]  
[Anonymous], 2001, PROBIOTIC FOOD HLTH
[2]   Effect of Probiotic Containing Ice-cream on Salivary Mutans Streptococci (SMS) Levels in Children of 6-12 Years of Age: A Randomized Controlled Double Blind Study with Six-months Follow Up [J].
Ashwin, Devasya ;
Vijayaprasad, K. E. ;
Taranath, Mahanthesh ;
Ramagoni, Naveen Kumar ;
Nara, Asha ;
Sarpangala, Mythri .
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2015, 9 (02) :ZC6-ZC9
[3]   Gastroenterology 1 - Inflammatory bowel disease: cause and immunobiology [J].
Baumgart, Daniel C. ;
Carding, Simon R. .
LANCET, 2007, 369 (9573) :1627-1640
[4]   A randomised, double-blind, placebo-controlled trial of a multi-strain probiotic in patients with asymptomatic ulcerative colitis and Crohn's disease [J].
Bjarnason, Ingvar ;
Sission, Guy ;
Hayee, Bu'Hussaine .
INFLAMMOPHARMACOLOGY, 2019, 27 (03) :465-473
[5]   Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Outpatients-A Systematic Review and Meta-Analysis [J].
Blaabjerg, Sara ;
Artzi, Daniel Maribo ;
Aabenhus, Rune .
ANTIBIOTICS-BASEL, 2017, 6 (04)
[6]  
Black F.T., 1989, Travel Medicine, V1, P333, DOI [10.1007/978-3-642-73772-5-70, 10.1007/978-3-642-73772-5_70, DOI 10.1007/978-3-642-73772-570]
[7]  
Bonifait L, 2009, J CAN DENT ASSOC, V75, P585
[8]  
BRUCE AW, 1973, CAN MED ASSOC J, V108, P973
[9]  
Carding Simon, 2015, Microbial Ecology in Health and Disease, V26, P26191, DOI 10.3402/mehd.v26.26191
[10]   Difference in the Gut Microbiome between Ovariectomy-Induced Obesity and Diet-Induced Obesity [J].
Choi, Sungmi ;
Hwang, Yu-Jin ;
Shin, Min-Jeong ;
Yi, Hana .
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2017, 27 (12) :2228-2236