Cyclometalated gold(III) complexes for chemoselective cysteine modification via ligand controlled C-S bond-forming reductive elimination

被引：92
作者：
Kung, Karen Ka-Yan
Ko, Hok-Ming
Cui, Jian-Fang
Chong, Hiu-Chi
Leung, Yun-Chung [1 ]
Wong, Man-Kin
机构：
[1] Hong Kong Polytech Univ, State Key Lab Chirosci, Hong Kong, Hong Kong, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 80期
关键词：
SELECTIVE PROTEIN MODIFICATION; AQUEOUS-MEDIUM; ORGANOGOLD(III) COMPLEXES; PEPTIDES; CATALYSIS; GOLD; REARRANGEMENTS; CHEMISTRY; MECHANISM; REAGENTS;
D O I：
10.1039/c4cc04467c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Modular assembly of cyclometalated gold(III) complexes by choosing appropriate bidentate C, N-donor ligands and ancillary ligands for chemoselective cysteine modification of peptides and proteins via C-S bond-forming reductive elimination has been achieved.
引用
收藏
页码：11899 / 11902
页数：4
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