Putting the squeeze on mephedrone hydrogen sulfate

被引：8

作者：

Satthaphut, Natsiri ^{[1
]}

Sutcliffe, Oliver B. ^{[2
]}

Oswald, Iain D. H. ^{[1
]}

机构：

[1] Univ Strathclyde, SIPBS, Glasgow G4 0RE, Lanark, Scotland

[2] Manchester Metropolitan Univ, Sch Sci & Environm, Manchester M1 5GD, Lancs, England

来源：

ZEITSCHRIFT FUR KRISTALLOGRAPHIE-CRYSTALLINE MATERIALS | 2014年 / 229卷 / 02期

基金：

英国工程与自然科学研究理事会;

关键词：

high pressure; illicit materials; polymorphism; single-crystal transition; PREDICTED CRYSTAL-STRUCTURES; X-RAY-DIFFRACTION; MOLECULAR-STRUCTURE; RAMAN-SPECTROSCOPY; LOW-TEMPERATURE; LEGAL HIGHS; PRESSURE; POLYMORPHISM; 2-CHLOROPHENOL; VISUALIZATION;

D O I：

10.1515/zkri-2013-1639

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

Herein we report the characterisation of a novel salt of the "legal high" (+/-)-4'-methylmethcathinone hydrogen sulfate and its polymorphism under ambient and high pressure conditions. Under ambient pressure only one polymorph of the title compound was isolated but when subjected to high pressure a further two polymorphs are observed. The phase transitions at >0.5 GPa and >3.6 GPa are reversible single crystal to single crystal transitions which is possible due to the similarity of the packing in the molecules. It is proposed that these transitions are driven by the pV term of the Gibbs Free Energy equation rather than by the relief of repulsive interactions between molecules.

引用

页码：101 / 111

页数：11

共 59 条

[1] Pressure-induced polymorphism in phenol [J].

Allan, DR ;

Clark, SJ ;

Dawson, A ;

McGregor, PA ;

Parsons, S .

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 2002, 58 (58) :1018-1024

[2] Structure of crystalline methanol at high pressure [J].

Allan, DR ;

Clark, SJ ;

Brugmans, MJP ;

Ackland, GJ ;

Vos, WL .

PHYSICAL REVIEW B, 1998, 58 (18) :11809-11812

[3] The Cambridge Structural Database: a quarter of a million crystal structures and rising [J].

Allen, FH .

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 2002, 58 (3 PART 1) :380-388

[4] SIR92 - a program for automatic solution of crystal structures by direct methods [J].

ALTOMARE, A ;

CASCARANO, G ;

GIACOVAZZO, G ;

GUAGLIARDI, A ;

BURLA, MC ;

POLIDORI, G ;

CAMALLI, M .

JOURNAL OF APPLIED CRYSTALLOGRAPHY, 1994, 27 :435-435

[5]

Anderson D. M., 2011, SOCIAL HARMS LEGISLA

[6] Polymorphism - A Perspective [J].

Bernstein, Joel .

CRYSTAL GROWTH & DESIGN, 2011, 11 (03) :632-650

[7] CRYSTALS version 12: software for guided crystal structure analysis [J].

Betteridge, PW ;

Carruthers, JR ;

Cooper, RI ;

Prout, K ;

Watkin, DJ .

JOURNAL OF APPLIED CRYSTALLOGRAPHY, 2003, 36 :1487-1487

[8] On the polymorphism of aspirin [J].

Bond, Andrew D. ;

Boese, Roland ;

Desiraju, Gautam R. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (04) :615-617

[9] Chemical analysis of four capsules containing the controlled substance analogues 4-methylmethcathinone, 2-fluoromethamphetamine, α-phthalimidopropiophenone and N-ethylcathinone [J].

Camilleri, Andrew ;

Johnston, Martin R. ;

Brennan, Michael ;

Davis, Sean ;

Caldicott, David G. E. .

FORENSIC SCIENCE INTERNATIONAL, 2010, 197 (1-3) :59-66

[10]

Ciezak J. A., J PHYS CHEM A

← 1 2 3 4 5 6 →