HTLV-1 tax hijacks cellular ubiquitination machinery to assemble K63-linked polyubiquitin for canonical NF-κB activation

被引：0
|
作者：
Ho, Yik-Khuan A. [1 ]
Zhi, Huijun [1 ]
Bowlin, Tara [1 ]
Dorjbal, Batsukh [1 ]
Philip, Subha [1 ]
Zahoor, Muhammad A. [1 ]
Shih, Hsiu-Ming [2 ]
Schaefer, Brian [1 ]
Glover, J. N. Mark [3 ]
Giam, Chou-Zen [1 ]
机构：
[1] Uniformed Serv Univ Hlth Sci, Dept Microbiol & Immunol, Bethesda, MD 20814 USA
[2] Acad Sinica, Inst Biomed Sci, Taipei 115, Taiwan
[3] Univ Alberta, Fac Med & Dent, Dept Biochem, Edmonton, AB T6G 2H7, Canada
来源：
RETROVIROLOGY | 2015年 / 12卷
关键词：
Ring Finger Protein; Basic Cellular Process; Centrosome Function; Ubiquitination Machinery; TAK1 Binding Protein;
D O I：
10.1186/1742-4690-12-S1-O34
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
O34
引用
收藏
页数：1
相关论文
共 50 条
  • [1] HTLV-1 tax hijacks cellular ubiquitination machinery to assemble K63-linked polyubiquitin for canonical NF-κB activation
    Yik-Khuan A Ho
    Huijun Zhi
    Tara Bowlin
    Batsukh Dorjbal
    Subha Philip
    Muhammad A Zahoor
    Hsiu-Ming Shih
    Brian Schaefer
    JN Mark Glover
    Chou-Zen Giam
    Retrovirology, 12
  • [2] HTLV-1 Tax impairs K63-linked ubiquitination of STING to evade host innate immunity.
    Wang, Jie
    Yang, Shuai
    Liu, Lu
    Wang, Hui
    Yang, Bo
    VIRUS RESEARCH, 2017, 232 : 13 - 21
  • [3] Modulation of HTLV-1 Tax Protein Ubiquitination by Cellular Optineurin: Functional Implications for the NF-?B Pathway Activation
    Journo, C.
    Gessain, A.
    Flynn, D.
    About, F.
    Filipe, J.
    Afonso, P., V
    Vidalain, P. O.
    Mahieux, R.
    Weil, R.
    Chevalier, S. A.
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2009, 25 (11) : 1228 - 1228
  • [4] CHIP promotes the activation of NF-κB signaling through enhancing the K63-linked ubiquitination of TAK1
    Yuchun Liu
    Yao Sun
    Shaoming Han
    Yanan Guo
    Qingnan Tian
    Qiang Ma
    Shoutao Zhang
    Cell Death Discovery, 7
  • [5] CHIP promotes the activation of NF-κB signaling through enhancing the K63-linked ubiquitination of TAK1
    Liu, Yuchun
    Sun, Yao
    Han, Shaoming
    Guo, Yanan
    Tian, Qingnan
    Ma, Qiang
    Zhang, Shoutao
    CELL DEATH DISCOVERY, 2021, 7 (01)
  • [6] HTLV-1 Tax Is a Critical Lipid Raft Modulator That Hijacks IκB Kinases to the Microdomains for Persistent Activation of NF-κB
    Huang, Jiannan
    Ren, Tong
    Guan, Hui
    Jiang, Yixing
    Cheng, Hua
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (10) : 6208 - 6217
  • [7] Persistent activation of NF-κB by the Tax transforming protein of HTLV-1:: hijacking cellular IκB kinases
    Sun, SC
    Ballard, DW
    ONCOGENE, 1999, 18 (49) : 6948 - 6958
  • [8] Persistent activation of NF-κB by the Tax transforming protein of HTLV-1: hijacking cellular IκB kinases
    Shao-Cong Sun
    Dean W Ballard
    Oncogene, 1999, 18 : 6948 - 6958
  • [9] Hepatitis B e Antigen Inhibits NF-κB Activity by Interrupting K63-Linked Ubiquitination of NEMO
    Wang, Yuan
    Cui, Lei
    Yang, Guifang
    Zhan, Jianbo
    Guo, Liang
    Chen, Yu
    Fan, Chengpeng
    Liu, Dan
    Guo, Deyin
    JOURNAL OF VIROLOGY, 2019, 93 (02)
  • [10] Regulation of NF-κB by the HTLV-1 Tax protein
    Li, XH
    Gaynor, RB
    GENE EXPRESSION, 1999, 7 (4-6): : 233 - 245
12345