In vitro antioxidant activity and solar protection factor of blackberry and raspberry extracts in topical formulation

被引：33

作者：

Cefali, Leticia Caramori ^{[1
]}

Franco, Julia Gomes ^{[2
]}

Nicolini, Giulia Ferreira ^{[2
]}

Ataide, Janaina Artem ^{[2
]}

Mazzola, Priscila Gava ^{[2
]}

机构：

[1] Univ Estadual Campinas, Inst Biol, UNICAMP, Campinas, SP, Brazil

[2] Univ Estadual Campinas, Fac Pharmaceut Sci, UNICAMP, Campinas, SP, Brazil

来源：

JOURNAL OF COSMETIC DERMATOLOGY | 2019年 / 18卷 / 02期

基金：

巴西圣保罗研究基金会;

关键词：

antioxidant; blackberry; flavonoids; raspberry; solar protection factor; BROMELAIN; NANOPARTICLES; CHITOSAN; ACID; NANOCAPSULES; FLAVONOIDS; ADSORPTION; STABILITY; BEHAVIOR; DRUGS;

D O I：

10.1111/jocd.12842

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

BackgroundBerries are known for their antioxidant activity due to the presence of flavonoids. Antioxidants' usage guarantees skin protection against free radicals and, flavonoids, especially, can act as sunscreen. The aim of this paper was to evaluate solar protection factor (SPF) and antioxidant activity in vitro of blackberry and raspberry extracts incorporated in topical formulation and study their stability. ResultsRaspberry presented 29.93mg of anthocyanins/100g of fruit and blackberry 65.58mg of anthocyanins/100g of fruit. In vitro solar protection factor was 54.57 to blackberry and 37.32 to raspberry. When incorporated in O/W emulsions, final formulations showed light pink color, creamy aspect, and typical fruity odor. Formulations submitted to indirect light and stove showed odor and color alterations. ConclusionsBased on the results, formulations containing extracts should be kept under refrigeration in opaque package to ensure stability due to the presence of flavonoids. In addition, blackberry and raspberry extracts are potential natural alternatives to be used as sunscreen and to prevent skin aging.

引用

页码：539 / 544

页数：6

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