Antidepressants, withdrawal, and addiction; where are we now?

被引:23
作者
Jauhar, Sameer [1 ]
Hayes, Joseph [2 ]
Goodwin, Guy M. [3 ]
Baldwin, David S. [4 ]
Cowen, Philip J. [3 ]
Nutt, David J. [5 ]
机构
[1] Kings Coll London, Dept Psychol Med, London, England
[2] UCL, Div Psychiat, London, England
[3] Univ Oxford, Dept Psychiat, Oxford, England
[4] Univ Southampton, Clin & Expt Sci, Southampton, Hants, England
[5] Imperial Coll London, London, England
基金
英国惠康基金;
关键词
Antidepressive agents; addiction; serotonin uptake inhibitors; paroxetine; DOUBLE-BLIND; DISCONTINUATION SYMPTOMS; ANXIETY DISORDER; PAROXETINE; INTERRUPTION; ESCITALOPRAM; FLUOXETINE; SAFETY;
D O I
10.1177/0269881119845799
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Controversy continues with regard to antidepressants and withdrawal. Recent debates have focused on the prevalence and length of withdrawal, and some continue to state that withdrawal from these compounds constitutes 'addiction'. In this editorial we examine the evidence underlying these recent debates. We acknowledge gaps in knowledge, and make suggestions for how the field can progress.
引用
收藏
页码:655 / 659
页数:5
相关论文
共 34 条
[1]  
[Anonymous], 2013, DIAGNOSTIC STAT MANU, VFifth, P1000, DOI [10.1176/appi.books.9780890425596, DOI 10.1176/APPI.BOOKS.9780890425596]
[2]  
[Anonymous], 2005, REPORT CSM EXPERT WO
[3]  
[Anonymous], 2015, BMJ BRIT MED J, DOI DOI 10.1136/BMJ.H4320
[4]   Escitalopram and paroxetine in the treatment of generalised anxiety disorder - Randomised, placebo-controlled, double-blind study [J].
Baldwin, David S. ;
Huusom, Anna Karina Trap ;
Maehlum, Eli .
BRITISH JOURNAL OF PSYCHIATRY, 2006, 189 :264-272
[5]   Discontinuation symptoms in depression and anxiety disorders [J].
Baldwin, David S. ;
Montgomery, Stuart A. ;
Nil, Rico ;
Lader, Malcolm .
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2007, 10 (01) :73-84
[6]   Selection Bias in Web Surveys [J].
Bethlehem, Jelke .
INTERNATIONAL STATISTICAL REVIEW, 2010, 78 (02) :161-188
[7]   A meta-analysis of response rates in Web- or internet-based surveys [J].
Cook, C ;
Heath, F ;
Thompson, RL .
EDUCATIONAL AND PSYCHOLOGICAL MEASUREMENT, 2000, 60 (06) :821-836
[8]   A systematic review into the incidence, severity and duration of antidepressant withdrawal effects: Are guidelines evidence-based? [J].
Davies, James ;
Read, John .
ADDICTIVE BEHAVIORS, 2019, 97 :111-121
[9]   Antidepressant tapering strips to help people come off medication more safely [J].
Groot, Peter C. ;
van Os, Jim .
PSYCHOSIS-PSYCHOLOGICAL SOCIAL AND INTEGRATIVE APPROACHES, 2018, 10 (02) :142-145
[10]   Do antidepressants have any potential to cause addiction? [J].
Haddad, P .
JOURNAL OF PSYCHOPHARMACOLOGY, 1999, 13 (03) :300-307