Racial and Ethnic Disparities in the Utilization of Thrombectomy for Acute Stroke Analysis of Data From 2016 to 2018

被引:106
作者
Rinaldo, Lorenzo [1 ]
Rabinstein, Alejandro A. [2 ]
Cloft, Harry [1 ,3 ]
Knudsen, John M. [3 ]
Castilla, Leonardo Rangel [1 ,3 ]
Brinjikji, Waleed [1 ,3 ]
机构
[1] Mayo Clin, Dept Neurosurg, Rochester, MN USA
[2] Mayo Clin, Dept Neurol, Rochester, MN USA
[3] Mayo Clin, Dept Radiol, Rochester, MN USA
关键词
insurance; Medicaid; patients; regression analysis; thrombectomy; ACUTE ISCHEMIC-STROKE; SOCIOECONOMIC DISPARITIES; ENDOVASCULAR THERAPY; MECHANICAL THROMBECTOMY; RACE; SEX;
D O I
10.1161/STROKEAHA.118.024651
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background and Purpose- Racial and ethnic disparities in the access to mechanical thrombectomy (MT) for treatment of acute ischemic stroke (AIS) secondary to large vessel occlusion have been previously described. The effect of recent randomized trials validating MT as an effective therapy for AIS secondary to large vessel occlusion on such disparities has not been investigated. Methods- Information on admissions for AIS to endovascular centers occurring between January 2016 and September 2018 was obtained from a national database. The number of patients receiving IV-tPA (intravenous tissue-type plasminogen activator) and MT at each institution was determined, and patient demographics were characterized according to age, sex, race/ethnicity, and insurance status. Comparisons of patients who did and did not undergo MT and between patients of different racial and ethnic backgrounds were performed. Demographic variables independently associated with the utilization of MT were identified using multivariate linear regression analysis. Results- There were 206 853 admissions to 173 endovascular centers during the time period of interest. The overall utilization of MT was 8.4%. The utilization of MT for black/Hispanic patients was lower than that among white/non-Hispanic patients (7.0% versus 9.8%; P<0.001). Black/Hispanic patients were also less likely to receive IV-tPA (16.2% versus 20.5%; P<0.001) and to be admitted to the endovascular center after transfer from a different hospital (20.0% versus 30.1%; P<0.001). On multivariate linear regression analysis, increasing institutional proportions of patients with female sex (beta=-0.601; P<0.001), insurance with Medicaid or uninsured status (beta=-0.153; P=0.029), and black/Hispanic race/ethnicity (beta=-0.062; P=0.046) were independently associated with lower institutional utilization of MT. Conclusions- Despite the mainstream acceptance of MT for the treatment of AIS secondary to large vessel occlusion, racial and ethnic disparities in the utilization of MT persist.
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收藏
页码:2428 / 2432
页数:5
相关论文
共 18 条
[1]   Racial and Socioeconomic Disparities in Access to Mechanical Revascularization Procedures for Acute Ischemic Stroke [J].
Attenello, Frank J. ;
Adamczyk, Peter ;
Wen, Ge ;
He, Shuhan ;
Zhang, Katie ;
Russin, Jonathan J. ;
Sanossian, Nerses ;
Amar, Arun P. ;
Mack, William J. .
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, 2014, 23 (02) :327-334
[2]   A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke [J].
Berkhemer, O. A. ;
Fransen, P. S. S. ;
Beumer, D. ;
van den Berg, L. A. ;
Lingsma, H. F. ;
Yoo, A. J. ;
Schonewille, W. J. ;
Vos, J. A. ;
Nederkoorn, P. J. ;
Wermer, M. J. H. ;
van Walderveen, M. A. A. ;
Staals, J. ;
Hofmeijer, J. ;
van Oostayen, J. A. ;
Nijeholt, G. J. Lycklama A. ;
Boiten, J. ;
Brouwer, P. A. ;
Emmer, B. J. ;
de Bruijn, S. F. ;
van Dijk, L. C. ;
Kappelle, L. J. ;
Lo, R. H. ;
Van Dijk, E. J. ;
de Vries, J. ;
de Kort, P. L. M. ;
van Rooij, W. J. J. ;
van den Berg, J. S. P. ;
van Hasselt, B. A. A. M. ;
Aerden, L. A. M. ;
Dallinga, R. J. ;
Visser, M. C. ;
Bot, J. C. J. ;
Vroomen, P. C. ;
Eshghi, O. ;
Schreuder, T. H. C. M. L. ;
Heijboer, R. J. J. ;
Keizer, K. ;
Tielbeek, A. V. ;
den Hertog, H. M. ;
Gerrits, D. G. ;
van den Berg-Vos, R. M. ;
Karas, G. B. ;
Steyerberg, E. W. ;
Flach, H. Z. ;
Marquering, H. A. ;
Sprengers, M. E. S. ;
Jenniskens, S. F. M. ;
Beenen, L. F. M. ;
van den Berg, R. ;
Koudstaal, P. J. .
NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (01) :11-20
[3]   Endovascular Therapy and Ethnic Disparities in Stroke Outcomes [J].
Bouslama, Mehdi ;
Rebello, Leticia C. ;
Haussen, Diogo C. ;
Grossberg, Jonathan A. ;
Anderson, Aaron M. ;
Belagaje, Samir R. ;
Bianchi, Nicolas A. ;
Frankel, Michael R. ;
Nogueira, Raul G. .
INTERVENTIONAL NEUROLOGY, 2018, 7 (06) :389-398
[4]   Socioeconomic Disparities in the Utilization of Mechanical Thrombectomy for Acute Ischemic Stroke in US Hospitals [J].
Brinjikji, W. ;
Rabinstein, A. A. ;
McDonald, J. S. ;
Cloft, H. J. .
AMERICAN JOURNAL OF NEURORADIOLOGY, 2014, 35 (03) :553-556
[5]   Socioeconomic Disparities in the Utilization of Mechanical Thrombectomy for Acute Ischemic Stroke [J].
Brinjikji, Waleed ;
Rabinstein, Alejandro A. ;
Cloft, Harry J. .
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, 2014, 23 (05) :979-984
[6]   Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging Selection [J].
Campbell, B. C. V. ;
Mitchell, P. J. ;
Kleinig, T. J. ;
Dewey, H. M. ;
Churilov, L. ;
Yassi, N. ;
Yan, B. ;
Dowling, R. J. ;
Parsons, M. W. ;
Oxley, T. J. ;
Wu, T. Y. ;
Brooks, M. ;
Simpson, M. A. ;
Miteff, F. ;
Levi, C. R. ;
Krause, M. ;
Harrington, T. J. ;
Faulder, K. C. ;
Steinfort, B. S. ;
Priglinger, M. ;
Ang, T. ;
Scroop, R. ;
Barber, P. A. ;
McGuinness, B. ;
Wijeratne, T. ;
Phan, T. G. ;
Chong, W. ;
Chandra, R. V. ;
Bladin, C. F. ;
Badve, M. ;
Rice, H. ;
de Villiers, L. ;
Ma, H. ;
Desmond, P. M. ;
Donnan, G. A. ;
Davis, S. M. .
NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (11) :1009-1018
[7]   Individual and System Contributions to Race and Sex Disparities in Thrombolysis Use for Stroke Patients in the United States [J].
Faigle, Roland ;
Urrutia, Victor C. ;
Cooper, Lisa A. ;
Gottesman, Rebecca F. .
STROKE, 2017, 48 (04) :990-997
[8]   Randomized Assessment of Rapid Endovascular Treatment of Ischemic Stroke [J].
Goyal, M. ;
Demchuk, A. M. ;
Menon, B. K. ;
Eesa, M. ;
Rempel, J. L. ;
Thornton, J. ;
Roy, D. ;
Jovin, T. G. ;
Willinsky, R. A. ;
Sapkota, B. L. ;
Dowlatshahi, D. ;
Frei, D. F. ;
Kamal, N. R. ;
Montanera, W. J. ;
Poppe, A. Y. ;
Ryckborst, K. J. ;
Silver, F. L. ;
Shuaib, A. ;
Tampieri, D. ;
Williams, D. ;
Bang, O. Y. ;
Baxter, B. W. ;
Burns, P. A. ;
Choe, H. ;
Heo, J. -H. ;
Holmstedt, C. A. ;
Jankowitz, B. ;
Kelly, M. ;
Linares, G. ;
Mandzia, J. L. ;
Shankar, J. ;
Sohn, S. -I. ;
Swartz, R. H. ;
Barber, P. A. ;
Coutts, S. B. ;
Smith, E. E. ;
Morrish, W. F. ;
Weill, A. ;
Subramaniam, S. ;
Mitha, A. P. ;
Wong, J. H. ;
Lowerison, M. W. ;
Sajobi, T. T. ;
Hill, M. D. .
NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (11) :1019-1030
[9]   Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials [J].
Goyal, Mayank ;
Menon, Bijoy K. ;
van Zwam, Wim H. ;
Dippel, Diederik W. J. ;
Mitchell, Peter J. ;
Demchuk, Andrew M. ;
Davalos, Antoni ;
Majoie, Charles B. L. M. ;
van der Lugt, Aad ;
de Miquel, Maria A. ;
Donnan, Geoff Rey A. ;
Roos, Yvo B. W. E. M. ;
Bonafe, Alain ;
Jahan, Reza ;
Diener, Hans-Christoph ;
van den Berg, Lucie A. ;
Levy, Elad I. ;
Berkhemer, Olvert A. ;
Pereira, Vitor M. ;
Rempel, Jeremy ;
Millan, Monica ;
Davis, Stephen M. ;
Roy, Daniel ;
Thornton, John ;
San Roman, Luis ;
Ribo, Marc ;
Beumer, Debbie ;
Stouch, Bruce ;
Brown, Scott ;
Campbell, Bruce C. V. ;
van Oostenbrugge, Robert J. ;
Saver, Jeff Rey L. ;
Hill, Michael D. ;
Jovin, Tudor G. .
LANCET, 2016, 387 (10029) :1723-1731
[10]   Thrombectomy within 8 Hours after Symptom Onset in Ischemic Stroke [J].
Jovin, T. G. ;
Chamorro, A. ;
Cobo, E. ;
de Miquel, M. A. ;
Molina, C. A. ;
Rovira, A. ;
San Roman, L. ;
Serena, J. ;
Abilleira, S. ;
Ribo, M. ;
Millan, M. ;
Urra, X. ;
Cardona, P. ;
Lopez-Cancio, E. ;
Tomasello, A. ;
Castano, C. ;
Blasco, J. ;
Aja, L. ;
Dorado, L. ;
Quesada, H. ;
Rubiera, M. ;
Hernandez-Perez, M. ;
Goyal, M. ;
Demchuk, A. M. ;
von Kummer, R. ;
Gallofre, M. ;
Davalos, A. .
NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (24) :2296-2306