Simplified analysis of mixtures of small molecules by chromatographic NMR spectroscopy

被引：48
作者：
Pages, Guilhem
Delaurent, Corinne
Caldarelli, Stefano
机构：
[1] Univ Aix Marseille 1, F-13397 Marseille 20, France
[2] Univ Aix Marseille 3, F-13397 Marseille, France
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 36期
关键词：
analytical methods; chromatography; diffusion; magic-angle spinning; NMR spectroscopy;
D O I：
10.1002/anie.200601622
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Figure Presented) Break it up: Ordinarily, silica gel produces no separation in a mixture of aromatic molecules by HPLC; however, solid-enhanced DOSY NMR spectroscopy succeeds in this task, although its separation capabilities concern just the spectral components. Chromatographic NMR spectroscopy may thus prove a simple complement to HPLC in favorable cases. MAS = magic-angle spinning. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.
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收藏
页码：5950 / 5953
页数：4
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