Age at natural menopause and risk of diabetes in adult women: Findings from the China Kadoorie Biobank study in the Zhejiang area

被引:23
作者
Wang, Meng [1 ]
Hu, Ru-Ying [1 ]
Wang, Hao [1 ]
Gong, Wei-Wei [1 ]
Wang, Chun-Mei [2 ]
Xie, Kai-Xu [2 ]
Chen, Zheng-Ming [3 ,4 ]
Guo, Yu [5 ]
Yu, Min [1 ]
Li, Li-Ming [6 ]
机构
[1] Zhejiang Prov Ctr Dis Control & Prevent, Dept NCDs Control & Prevent, Hangzhou, Zhejiang, Peoples R China
[2] Tongxiang Ctr Dis Control & Prevent, Tongxiang, Peoples R China
[3] Univ Oxford, Nuffield Dept Populat Hlth, Clin Trial Serv Unit, Oxford, England
[4] Univ Oxford, Nuffield Dept Populat Hlth, Epidemiol Studies Unit CTSU, Oxford, England
[5] Chinese Acad Med Sci, Beijing, Peoples R China
[6] Peking Univ, Dept Epidemiol, Hlth Sci Ctr, Sch Publ Hlth, Beijing, Peoples R China
基金
英国惠康基金; 中国国家自然科学基金;
关键词
Age; Diabetes; Menopause; POSTMENOPAUSAL WOMEN; REPRODUCTIVE FACTORS; INSULIN LEVELS; FOLLOW-UP; ASSOCIATION; HEALTH; GLUCOSE; CANCER; COHORT; METAANALYSIS;
D O I
10.1111/jdi.12775
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aims/IntroductionThere has been considerable professional debate on the association between age at menopause and diabetes risk, while the findings are controversial. The present study explored the association between late menopause and the prevalence of diabetes in the Chinese population. Material and MethodsThe data were part of the baseline survey of China Kadoorie Biobank from Zhejiang Province. A total of 17,076 postmenopausal women were included in the present study. Logistic regression models were used to calculate the adjusted odds ratios and their 95% confidence intervals. ResultsOf the participating women, 1,288 (7.54%) had type 2 diabetes. In comparison with those with menopause at 46-52 years, women with menopause at a later age (53 years) were 1.21-fold (95% confidence interval 1.03-1.43) more likely to have diabetes. ConclusionsThe present findings suggested that later age at menopause was associated with an increased prevalence of diabetes.
引用
收藏
页码:762 / 768
页数:7
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