PHYLOGENETIC CONFIDENCE INTERVALS FOR THE OPTIMAL TRAIT VALUE

被引:12
作者
Bartoszek, Krzysztof [1 ]
Sagitov, Serik [2 ,3 ]
机构
[1] Uppsala Univ, Dept Math, S-75106 Uppsala, Sweden
[2] Chalmers Univ Technol, Dept Math Sci, S-41296 Gothenburg, Sweden
[3] Univ Gothenburg, S-41296 Gothenburg, Sweden
基金
瑞典研究理事会;
关键词
Central limit theorem; conditionedYule process; macroevolution; martingales; Ornstein-Uhlenbeck process; phylogenetics; INTERSPECIES CORRELATION; BRANCH LENGTHS; EVOLUTION; TREES; MODELS; TIME; DIVERSITY;
D O I
10.1017/S0021900200113117
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
We consider a stochastic evolutionary model for a phenotype developing amongst n related species with unknown phylogeny. The unknown tree is modelled by a Yule process conditioned on n contemporary nodes. The trait value is assumed to evolve along lineages as an Ornstein-Uhlenbeck process. As a result, the trait values of the n species form a sample with dependent observations. We establish three limit theorems for the sample mean corresponding to three domains for the adaptation rate. In the case of fast adaptation, we show that for large n the normalized sample mean is approximately normally distributed. Using these limit theorems, we develop novel confidence interval formulae for the optimal trait value.
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页码:1115 / 1132
页数:18
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