Quinone analogs prevent enzymes targeted in Friedreich ataxia from iron-induced injury in vitro

被引：25

作者：

Rustin, P ^{[1
]}

Munnich, A ^{[1
]}

Rötig, A ^{[1
]}

机构：

[1] Hop Necker Enfants Malad, Unite Rech Handicaps Genet Enfant, INSERM, U393, F-75743 Paris 15, France

来源：

BIOFACTORS | 1999年 / 9卷 / 2-4期

关键词：

D O I：

10.1002/biof.5520090220

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：247 / 251

页数：5

共 20 条

[1] Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin [J].

Babcock, M ;

deSilva, D ;

Oaks, R ;

DavisKaplan, S ;

Jiralerspong, S ;

Montermini, L ;

Pandolfo, M ;

Kaplan, J .

SCIENCE, 1997, 276 (5319) :1709-1712

[2] Friedreich's ataxia: Autosomal recessive disease caused by an intronic GAA triplet repeat expansion [J].

Campuzano, V ;

Montermini, L ;

Molto, MD ;

Pianese, L ;

Cossee, M ;

Cavalcanti, F ;

Monros, E ;

Rodius, F ;

Duclos, F ;

Monticelli, A ;

Zara, F ;

Canizares, J ;

Koutnikova, H ;

Bidichandani, SI ;

Gellera, C ;

Brice, A ;

Trouillas, P ;

DeMichele, G ;

Filla, A ;

DeFrutos, R ;

Palau, F ;

Patel, PI ;

DiDonato, S ;

Mandel, JL ;

Cocozza, S ;

Koenig, M ;

Pandolfo, M .

SCIENCE, 1996, 271 (5254) :1423-1427

[3]

CHAMBERLAIN S, 1989, AM J HUM GENET, V44, P518

[4] BIOCHEMICAL, PHYSIOLOGICAL AND MEDICAL ASPECTS OF UBIQUINONE FUNCTION [J].

ERNSTER, L ;

DALLNER, G .

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1995, 1271 (01) :195-204

[5] Deletion of the yeast homologue of the human gene associated with Friedreich's ataxia elicits iron accumulation in mitochondria [J].

Foury, F ;

Cazzalini, O .

FEBS LETTERS, 1997, 411 (2-3) :373-377

[6]

GARCIARUIZ C, 1995, MOL PHARMACOL, V48, P825

[7] ACONITASE IS A SENSITIVE AND CRITICAL TARGET OF OXYGEN POISONING IN CULTURED-MAMMALIAN-CELLS AND IN RAT LUNGS [J].

GARDNER, PR ;

NGUYEN, DDH ;

WHITE, CW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (25) :12248-12252

[8]

GEOFFROY G, 1976, Canadian Journal of Neurological Sciences, V3, P279

[9] IDEBENONE - A REVIEW OF ITS PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES, AND THERAPEUTIC USE IN AGE-RELATED COGNITIVE DISORDERS [J].

GILLIS, JC ;

BENFIELD, P ;

MCTAVISH, D .

DRUGS & AGING, 1994, 5 (02) :133-152

[10] OXYGEN-TOXICITY, OXYGEN RADICALS, TRANSITION-METALS AND DISEASE [J].

HALLIWELL, B ;

GUTTERIDGE, JMC .

BIOCHEMICAL JOURNAL, 1984, 219 (01) :1-14

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