Lewis Acid Catalyzed Inverse-Electron-Demand Diels-Alder Reaction of Tropones

被引：103

作者：

Li, Pingfan ^{[1
]}

Yamamoto, Hisashi ^{[1
]}

机构：

[1] Univ Chicago, Dept Chem, Chicago, IL 60637 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 131卷 / 46期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

ASYMMETRIC CLAISEN REARRANGEMENT; CHIRAL ORGANOALUMINUM REAGENT; PERFLUOROPHENYL DERIVATIVES; VINYL ETHERS; RING-SYSTEM; ALDOL-TYPE; TRIS(PENTAFLUOROPHENYL)BORON; CYCLOADDITIONS; EFFICIENT; CP-225,917;

D O I：

10.1021/ja908127f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Lewis acid catalyzed inverse-electron-demand Diets-Alder reaction of tropone derivatives was developed. Up to 97% ee was obtained for the chiral dinucleus BINOL-aluminum complex catalyzed reaction between tropones and ketene diethyl acetal to give bicyclo[3.2.2] ring structures, which opens up a unique way of making chiral seven-membered rings.

引用

页码：16628 / +

页数：3

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