Consensus statements and recommendations from the ESO-Karolinska Stroke Update Conference, Stockholm 11-13 November 2018

被引：137

作者：

Ahmed, Niaz ^{[1
,2
]}

Audebert, Heinrich ^{[3
,4
]}

Turc, Guillaume ^{[5
,6
,7
]}

Cordonnier, Charlotte ^{[8
]}

Christensen, Hanne ^{[9
,10
]}

Sacco, Simona ^{[11
]}

Sandset, Else Charlotte ^{[12
]}

Ntaios, George ^{[13
]}

Charidimou, Andreas ^{[14
]}

Toni, Danilo ^{[15
]}

Pristipino, Christian ^{[16
]}

Koehrmann, Martin ^{[17
,18
]}

Kuramatsu, Joji B. ^{[19
]}

Thomalla, Geotz ^{[20
]}

Mikulik, Robert ^{[21
,22
,23
]}

Ford, Gary A. ^{[24
]}

Marti-Fabregas, Joan ^{[25
]}

Fischer, Urs ^{[26
]}

Thoren, Magnus ^{[1
,2
]}

Lundstrom, Erik ^{[27
]}

Rinkel, Gabriel J. E. ^{[28
]}

van der Worp, H. Bart ^{[28
]}

Matusevicius, Marius ^{[29
]}

Tsivgoulis, Georgios ^{[30
]}

Milionis, Haralampos ^{[31
]}

Rubiera, Marta ^{[32
]}

Hart, Robert ^{[33
]}

Moreira, Tiago ^{[1
,2
]}

Lantz, Maria ^{[1
,2
]}

Sjostrand, Christina ^{[1
,2
]}

Andersen, Grethe ^{[34
]}

Schellinger, Peter ^{[35
,36
]}

Kostulas, Konstantinos ^{[1
,2
]}

Sunnerhagen, Katharina Stibrant ^{[37
]}

Keselman, Boris ^{[1
,2
]}

Korompoki, Eleni ^{[38
]}

Purrucker, Jan ^{[39
]}

Khatri, Pooja ^{[40
]}

Whiteley, William ^{[41
]}

Berge, Eivind ^{[42
]}

Mazya, Michael ^{[1
,2
]}

Dippel, Diederik W. J. ^{[43
]}

Mustanoja, Satu ^{[44
]}

Rasmussen, Mads ^{[45
]}

Soderqvist, Asa Kuntze ^{[2
,46
]}

Escudero-Martinez, Irene ^{[47
,48
]}

Steiner, Thorsten ^{[39
,49
]}

机构：

[1] Karolinska Inst, Karolinska Univ Hosp, Dept Neurol, Stockholm, Sweden

[2] Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden

[3] Charite Univ Med Berlin, Dept Neurol, Hindenburgdamm 30, D-12203 Berlin, Germany

[4] Charite Univ Med Berlin, Ctr Stroke Res, Berlin, Germany

[5] GHU Paris Psychiat & Neurosci, Dept Neurol, Paris, France

[6] Univ Paris, Paris, France

[7] INSERM U1266, Paris, France

[8] Roger Salengro Hosp, Dept Neurol, Stroke Unit, F-59037 Lille, France

[9] Bispebjerg Hosp, Dept Neurol Neurol, Copenhagen, Denmark

[10] Frederiksberg Univ Hosp, Dept Neurol Neurol, Copenhagen, Denmark

[11] Univ LAlquila, Dept Appl Clin Sci & Biotechnol, Sect Neurol, Lalquila, Italy

[12] Oslo Univ Hosp, Dept Neurol, Oslo, Norway

[13] Univ Thessaly, Sch Med, Dept Internal Med, Larissa Univ Hosp, Biopolis, Larissa, Greece

[14] Harvard Med Sch, Dept Neurol, Massachusetts Gen Hosp, Stroke Res Ctr, Boston, MA 02115 USA

[15] SapienzaUniv, Dept Human Neurosci, Emergency Dept, Stroke Unit Hosp,Policlin Umberto 1, Rome, Italy

[16] San Filippo Neri ASL RMI Hosp, Intervent Cardiol Unit, Rome, Italy

[17] Univ Klinikum Erlangen, Dept Neurol, Essen, Germany

[18] Univ Duisburg Essen, Dept Neurol, Essen, Germany

[19] Univ Hosp Erlangen, Dept Neurol, Erlangen, Germany

[20] Univ Med Ctr Hamburg Eppendorf, Dept Neurol, Hamburg, Germany

[21] Masaryk Univ, Int Clin Res Ctr, St Annes Univ Hosp Brno, Brno, Czech Republic

[22] Masaryk Univ, Dept Neurol, St Annes Univ Hosp Brno, Brno, Czech Republic

[23] Masaryk Univ, Med Fac, Brno, Czech Republic

[24] Univ Oxford, 0Xford Univ Hosp NHS Fdn Trust, Oxford, England

[25] Hosp Santa Creu & Sant Pau, Biomed Res Inst St Pau IIB St Pau, Dept Neurol, Barcelona, Spain

[26] Univ Bern, Stroke Ctr Bern, Clin Trial Unit Bern, Bern, Switzerland

[27] Uppsala Univ, Dept Neurosci, Neurol, Akad Sjukhuset, Uppsala, Sweden

[28] Univ Med Ctr Utrecht, Brain Ctr, Dept Neurol & Neurosurg, Utrecht, Netherlands

[29] Karolinska Inst, Karolinska Univ Hosp, Dept Clin Neurosci, Stockholm, Sweden

[30] Natl & Kapodistrian Univ Athens, Dept Neurol 2, Athens, Greece

[31] Univ Ioannina, Sch Med, Dept Internal Med, Ioannina, Greece

[32] Vall dHebron Hosp, Dept Neurol, Barcelona, Spain

[33] Hamilton Hlth Sci, Populat Hlth Res Inst, Hamilton, ON, Canada

[34] Aarhus Univ Hosp, Dept Neurol, Aarhus, Denmark

[35] Ruhr Univ Bochum, John Wesling Med Ctr Minden, Dept Neurol, Minden, Germany

[36] Ruhr Univ Bochum, John Wesling Med Ctr Minden, Dept Neurogeriatry, Minden, Germany

[37] Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Clin Neurosci, Gothenburg, Sweden

[38] Alexandra Hosp, Med Sch Athens, Dept Clin Therapeut, Athens, Greece

[39] Heidelberg Univ Hosp, Dept Neurol, Heidelberg, Germany

[40] Univ Cincinnati, Med Ctr, Dept Neurol, Cincinnati, OH 45221 USA

[41] Univ Edinburgh, Ctr Clin Brain Sci, Edinburgh, Midlothian, Scotland

[42] Oslo Univ Hosp, Dept Internal Med & Cardiol, Oslo, Norway

[43] Erasmus MC Univ Med Ctr, Rotterdam, Netherlands

[44] Univ Helsinki, Cent Hosp, Dept Neurol, Helsinki, Finland

[45] Aarhus Univ Hosp, Dept Anaesthesia & Intens Care, Sect Neuroanaesthesia, Aarhus, Denmark

[46] Karolinska Univ Hosp, Dept Neuroradiol, Stockholm, Sweden

[47] Virgen del Rocio Univ Hosp, Dept Neurol, Seville, Spain

[48] Inst Biomed Sevilla, Seville, Spain

[49] Klinikum Frankfurt Hochst, Dept Neurol, Frankfurt, Germany

来源：

EUROPEAN STROKE JOURNAL | 2019年 / 4卷 / 04期

关键词：

Stroke; thrombolysis; thrombectomy; oral anticoagulation; patent foramen ovale; prehospital; intracerebral haemorrhage; ischaemic stroke;

D O I：

10.1177/2396987319863606

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The purpose of the European Stroke Organisation-Karolinska Stroke Update Conference is to provide updates on recent stroke therapy research and to give an opportunity for the participants to discuss how these results may be implemented into clinical routine. The meeting started 22 years ago as Karolinska Stroke Update, but since 2014 it is a joint conference with European Stroke Organisation. Importantly, it provides a platform for discussion on the European Stroke Organisation guidelines process and on recommendations to the European Stroke Organisation guidelines committee on specific topics. By this, it adds a direct influence from stroke professionals otherwise not involved in committees and work groups on the guideline procedure. The discussions at the conference may also inspire new guidelines when motivated. The topics raised at the meeting are selected by the scientific programme committee mainly based on recent important scientific publications. This year's European Stroke Organisation-Karolinska Stroke Update Meeting was held in Stockholm on 11-13 November 2018. There were 11 scientific sessions discussed in the meeting including two short sessions. Each session except the short sessions produced a consensus statement (Full version with background, issues, conclusions and references are published as web-material and at and ) and recommendations which were prepared by a writing committee consisting of session chair(s), scientific secretary and speakers. These statements were presented to the 250 participants of the meeting. In the open meeting, general participants commented on the consensus statement and recommendations and the final document were adjusted based on the discussion from the general participants Recommendations (grade of evidence) were graded according to the 1998 Karolinska Stroke Update meeting with regard to the strength of evidence. Grade A Evidence: Strong support from randomised controlled trials and statistical reviews (at least one randomised controlled trial plus one statistical review). Grade B Evidence: Support from randomised controlled trials and statistical reviews (one randomised controlled trial or one statistical review). Grade C Evidence: No reasonable support from randomised controlled trials, recommendations based on small randomised and/or non-randomised controlled trials evidence.

引用

页码：307 / 317

页数：11