The reaction of 1,2-diones with ureas - a synthesis of 4-(1-substituted)alkylimidazol-2-ones

被引：5

作者：

Liepa, AJ ^{[1
]}

Wright, DMJ ^{[1
]}

机构：

[1] CSIRO Mol Sci, Clayton, Vic 3169, Australia

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 2000年 / 53卷 / 01期

关键词：

synthesis; ureas; thioureas; imidazolones; diones; glyoxal;

D O I：

10.1071/CH99130

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction between glyoxal and ureas or thioureas in formic acid in the presence of sulfinates gives 4-arylsulfonylimidazol-2-ones such as (3b) and (3e). Labile 4-arylsulfonyl-5-hydroxyimidazolidin-2-ones (2a-c) may be isolated. Acyclic or cyclic 1,2-diketones react with ureas in the presence of selected nucleophiles to give side-chain substituted imidazol-2-ones (5a-e).

引用

页码：73 / 76

页数：4

共 5 条

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[3]

PETERSEN H, 1969, LIEBIGS ANN CHEM, V726, P89

[4]

SHUTALEV AD, 1996, CHEM HETEROCYCL COMP, V10, P1147

[5]

SPECKAMP WN, 1981, RECL TRAV CHIM PAY B, V100, P345

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