A role for antigen in the maintenance of immunological memory

被引：97
作者：
Gray, D [1 ]
机构：
[1] Univ Edinburgh, Ashworth Labs, Inst Cell Anim & Populat Biol, Edinburgh EH9 3JT, Midlothian, Scotland
来源：
NATURE REVIEWS IMMUNOLOGY | 2002年 / 2卷 / 01期
基金：
英国惠康基金; 英国医学研究理事会;
关键词：
D O I：
10.1038/nri706
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The immune system has a memory that it exhibits in the enhanced and augmented responses the second time it meets an antigen. The memory is the result of a number of changes to the system brought about during the primary response. The most important of these changes is the formation of an expanded pool of antigen-specific memory cells. One of the enduring questions in immunology is how these memory cells are maintained for such long periods.
引用
收藏
页码：60 / 65
页数：6
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