Multi-Component One-Pot Reactions for the Synthesis of Spirooxindole-pyrano[2,3-c]pyrazole Derivatives

被引：2
|
作者：
Feng, Jun [1 ]
Ablajan, Keyume [1 ]
Ma, Xiabing [1 ]
Li, Wenbo [1 ]
Obul, Mamateli [1 ]
机构：
[1] Xinjiang Univ, Coll Chem & Chem Engn, Minist Educ & Xinjiang Uyghur Autonomous Reg, Key Lab Oil & Gas Fine Chem, Urumqi 830046, Peoples R China
来源：
CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2016年 / 36卷 / 01期
基金：
中国国家自然科学基金;
关键词：
spirooxindole; multi-component reaction; one-pot synthesis; pyrano[2,3-c]pyrazole; REGIOSELECTIVE SYNTHESIS; L-PROLINE; EFFICIENT; CYCLIZATION; CONVENIENT; ACCESS; FACILE;
D O I：
10.6023/cjoc201507011
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A highly efficient strategy for the one-pot synthesis of multi-substituted spirooxindol-pyrano[2,3-c]pyrazole derivatives was developed. The product formed in good yield from the reaction of acetylenedicarboxylate, hydrazine, isatin, and (E)-1-methylthio-1-methylamino-2-nitroethylene in the presence of Et3N catalyst. This simple and convenient method could also be used to prepare similar types of product.
引用
收藏
页码：222 / 228
页数：7
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