How Tat targets TAR: Structure of the BIV peptide RNA complex

被引：23

作者：

Greenbaum, NL

机构：

[1] Dept. Biochem. and Molec. Biophys., Columbia University, College of Physicians and Surgeons, New York, NY 10032

来源：

STRUCTURE | 1996年 / 4卷 / 01期

关键词：

D O I：

10.1016/S0969-2126(96)00003-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two new NMR structures describing the complex formed by a peptide from the BIV Tat protein with the TAR RNA provide a significant advance in our understanding of the ways in which peptides interact with specific sites in the major groove of their RNA targets.

引用

页码：5 / 9

页数：5

共 18 条

[11]

KARN J, 1994, RNA PROTEIN INTERACT, P193

[12] SEQUENCE-SPECIFIC CLEAVAGE OF DOUBLE HELICAL DNA BY TRIPLE HELIX FORMATION [J].

MOSER, HE ;

DERVAN, PB .

SCIENCE, 1987, 238 (4827) :645-650

[13] CRYSTAL-STRUCTURE AT 1.92 ANGSTROM RESOLUTION OF THE RNA-BINDING DOMAIN OF THE U1A SPLICEOSOMAL PROTEIN COMPLEXED WITH AN RNA HAIRPIN [J].

OUBRIDGE, C ;

ITO, N ;

EVANS, PR ;

TEO, CH ;

NAGAI, K .

NATURE, 1994, 372 (6505) :432-438

[14] SOLUTION STRUCTURE OF A BOVINE IMMUNODEFICIENCY VIRUS TAT-TAR PEPTIDE-RNA COMPLEX [J].

PUGLISI, JD ;

CHEN, L ;

BLANCHARD, S ;

FRANKEL, AD .

SCIENCE, 1995, 270 (5239) :1200-1203

[15] CONFORMATION OF THE TAR RNA-ARGININE COMPLEX BY NMR-SPECTROSCOPY [J].

PUGLISI, JD ;

TAN, RY ;

CALNAN, BJ ;

FRANKEL, AD ;

WILLIAMSON, JR .

SCIENCE, 1992, 257 (5066) :76-80

[16] RNA RECOGNITION BY TAT-DERIVED PEPTIDES - INTERACTION IN THE MAJOR GROOVE [J].

WEEKS, KM ;

CROTHERS, DM .

CELL, 1991, 66 (03) :577-588

[17] STRUCTURE OF THE EQUINE INFECTIOUS-ANEMIA VIRUS TAT PROTEIN [J].

WILLBOLD, D ;

ROSINARBESFELD, R ;

STICHT, H ;

FRANK, R ;

ROSCH, P .

SCIENCE, 1994, 264 (5165) :1584-1587

[18] Molecular recognition in the bovine immunodeficiency virus Tat peptide TAR RNA complex [J].

Ye, XM ;

Kumar, RA ;

Patel, DJ .

CHEMISTRY & BIOLOGY, 1995, 2 (12) :827-840

← 1 2 →