Measurements of depolarization distribution in the healthy human macula by polarization sensitive OCT

被引：36

作者：

Baumann, Bernhard ^{[1
]}

Goetzinger, Erich ^{[1
]}

Pircher, Michael ^{[1
]}

Hitzenberger, Christoph K. ^{[1
]}

机构：

[1] Med Univ Vienna, Ctr Biomed Engn & Phys, A-1090 Vienna, Austria

来源：

JOURNAL OF BIOPHOTONICS | 2009年 / 2卷 / 6-7期

基金：

奥地利科学基金会;

关键词：

optical coherence tomography; polarization; retina; depolarization; retinal pigment epithelium; OPTICAL COHERENCE TOMOGRAPHY; NERVE-FIBER LAYER; RETINAL-PIGMENT EPITHELIUM; IMAGING POLARIMETRY; IN-VIVO; RESOLVED BIREFRINGENCE; MORPHOMETRIC-ANALYSIS; IMPROVED CONTRAST; DEGENERATION; TISSUE;

D O I：

10.1002/jbio.200910031

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Polarization sensitive optical coherence tomography (PS-OCT) allows for depth resolved imaging of polarization properties of retinal structures. Different layers in the retina can be distinguished not only based on their reflectivity but also due to their birefringent, depolarizing or polarization preserving character. In contrast to other structures in the posterior segment, the retinal pigment epithelium (RPE) is depolarizing, i.e., it scrambles the polarization state of light. A spectral domain (SD) PS-OCT system was used to record 3D data sets of the retina. The depolarizing effect of the RPE was analyzed by quantitative evaluation of the spatial depolarization distribution in the macula regions of healthy eyes. Depolarization in the RPE is most pronounced close to the center of the fovea and decreases with eccentricity. [GRAPHICS] Depolarization pattern in the human macula measured with PS-OCT (C) 2009 by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

引用

页码：426 / 434

页数：9

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