Surrogate Markers of Abdominal Aortic Aneurysm Progression

被引：68

作者：

Wanhainen, Anders ^{[1
]}

Mani, Kevin ^{[1
]}

Golledge, Jonathan ^{[2
,3
]}

机构：

[1] Uppsala Univ, Vasc Surg Sect, Dept Surg Sci, S-75185 Uppsala, Sweden

[2] James Cook Univ, Coll Med & Dent, Vasc Biol Unit, Queensland Res Ctr Peripheral Vasc Dis, Townsville, Qld 4811, Australia

[3] Townsville Hosp, Dept Vasc & Endovasc Surg, Townsville, Qld, Australia

来源：

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY | 2016年 / 36卷 / 02期

关键词：

aortic aneurysm; abdominal; biomarkers; magnetic resonance imaging; molecular imaging; ultrasonography; FINITE-ELEMENT-ANALYSIS; FOLLOW-UP; RUPTURE RISK; WALL STRESS; SURVEILLANCE INTERVALS; ULTRASOUND MEASUREMENT; VOLUME MEASUREMENTS; GROWTH-RATE; DIAMETER; EXPANSION;

D O I：

10.1161/ATVBAHA.115.306538

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The natural course of many abdominal aortic aneurysms (AAA) is to gradually expand and eventually rupture and monitoring the disease progression is essential to their management. In this publication, we review surrogate markers of AAA progression. AAA diameter remains the most widely used and important marker of AAA growth. Standardized reporting of reproducible methods of measuring AAA diameter is essential. Newer imaging assessments, such as volume measurements, biomechanical analyses, and functional and molecular imaging, as well as circulating biomarkers, have potential to add important information about AAA progression. Currently, however, there is insufficient evidence to recommend their routine use in clinical practice.

引用

页码：236 / 244

页数：9

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