Performance and use of current sheet antennae for RF-hyperthermia of a phantom monitored by 3 tesla MR-thermography

被引:7
作者
Hoffmann, W
Rhein, KH
Wojcik, F
Noeske, R
Seifert, F
Wlodarczyk, W
Fähling, H
Wust, P
Rinneberg, H
机构
[1] Phys Tech Bundesanstalt, D-10587 Berlin, Germany
[2] Humboldt Univ, Charite, Klin Strahlenheilkunde, D-13344 Berlin, Germany
关键词
hyperthermia; current sheet antennae; calorimetry; magnetic resonance thermography;
D O I
10.1080/02656730210129754
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Several MR-compatible current sheet antennae (CSA) of different height. (h) (16 cm (l) x 8 cm. (w) x 1-5 cm. (h)) were built for simulated RF (96 MHz) hyperthermia of a medium-sized (12 l) tissue-equivalent phantom inside a 3 tesla whole body tomograph. Prior to use, efficiencies of the CSA were determined by network analysis and by calorimetry. Depending on the height h of the CSA and on the thickness d(bolus) of the water bolus used for RF-coupling of the CSA to the lossy medium, their efficiency varied between 20-70% and the CSA with h = 3 cm was selected for simulated RF hyperthermia. During heating, spatial temperature distributions (20-42degreesC) of five slices (voxel size 2 x 2 x 10 mm(3)) were recorded intermittently within 4 s/slice by measuring the temperature dependent shift of the H-1 resonance frequency (125.32 MHz). A phased array consisting of two identical CSA produced distinctly different spatial temperature distributions at 0 and 1808 phase difference between both RF channels feeding the antennae. Within a one-dimensional heat diffusion model, the specific absorption rate. (SAR) of the electromagnetic wave generated by a single antenna was deduced from the experimental data resulting in a penetration depth. (1/e(2)) of similar to4 cm.
引用
收藏
页码:454 / 471
页数:18
相关论文
共 18 条
[1]  
BACHANDERSEN J, 1986, PHYS TECH, P66
[2]  
BACHANDERSEN J, 1986, PHYS TECH, P85
[3]   Magnetic resonance thermometry during hyperthermia for human high-grade sarcoma [J].
Carter, DL ;
MacFall, JR ;
Clegg, ST ;
Wan, X ;
Prescott, DM ;
Charles, HC ;
Samulski, TV .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1998, 40 (04) :815-822
[4]   CURRENT SHEET APPLICATOR ARRAYS FOR SUPERFICIAL HYPERTHERMIA OF CHESTWALL LESIONS [J].
GOPAL, MK ;
HAND, JW ;
LUMORI, MLD ;
ALKHAIRI, S ;
PAULSEN, KD ;
CETAS, TC .
INTERNATIONAL JOURNAL OF HYPERTHERMIA, 1992, 8 (02) :227-240
[5]   CURRENT SHEET APPLICATORS FOR CLINICAL MICROWAVE HYPERTHERMIA [J].
GOPAL, MK ;
CETAS, TC .
IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES, 1993, 41 (03) :431-437
[6]   PROTON RESONANCE SHIFT OF WATER IN GAS AND LIQUID STATES [J].
HINDMAN, JC .
JOURNAL OF CHEMICAL PHYSICS, 1966, 44 (12) :4582-&
[7]  
JAMES JR, 1986, PHYS TECH, P157
[8]   A NEW TYPE OF LIGHTWEIGHT LOW-FREQUENCY ELECTROMAGNETIC HYPERTHERMIA APPLICATOR [J].
JOHNSON, RH ;
PREECE, AW ;
HAND, JW ;
JAMES, JR .
IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES, 1987, 35 (12) :1317-1321
[9]  
JOHNSON RH, 1986, IEEE ELECT LETT, V22, P591
[10]   TEMPERATURE-DEPENDENCE OF CANINE BRAIN-TISSUE DIFFUSION-COEFFICIENT MEASURED IN-VIVO WITH MAGNETIC-RESONANCE ECHO-PLANAR IMAGING [J].
MACFALL, J ;
PRESCOTT, DM ;
FULLAR, E ;
SAMULSKI, TV .
INTERNATIONAL JOURNAL OF HYPERTHERMIA, 1995, 11 (01) :73-86