Sila-rhubafuran and Derivatives: Synthesis and Olfactory Characterization of Novel Silicon-Containing Odorants

被引：23

作者：

Foerster, Bettina ^{[1
]}

Bertermann, Ruediger ^{[1
]}

Kraft, Philip ^{[2
]}

Tacke, Reinhold ^{[1
]}

机构：

[1] Univ Wurzburg, Inst Anorgan Chem, D-97074 Wurzburg, Germany

[2] Givaudan Schweiz AG, Fragrance Res, CH-8600 Dubendorf, Switzerland

来源：

ORGANOMETALLICS | 2014年 / 33卷 / 01期

关键词：

DESIGN;

D O I：

10.1021/om401070c

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Sila-rhubafuran (1b), a silicon analogue of the grapefruit odorant rhubafuran (1a), was synthesized and isolated as a 1:1 mixture of two racemic diastereomers. In addition, the structurally related racemic C/Si pairs 2a/2b and 3a/3b were prepared. To get information about structure-odor relationships in the domain of grapefruit odorants, the C/Si pairs 1a/1b, 2a/2b, and 3a/3b were studied for their olfactory properties.

引用

页码：338 / 346

页数：9

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