To adhere or not to adhere: Rates and reasons of medication adherence in hematological cancer patients

被引：54
作者：
Hall, Alix E. [1 ,2 ]
Paul, Chris [1 ,2 ]
Bryant, Jamie [1 ,2 ]
Lynagh, Marita C. [1 ,2 ]
Rowlings, Philip [3 ,4 ]
Enjeti, Anoop [3 ,4 ]
Small, Hannah [1 ,2 ]
机构：
[1] Univ Newcastle, Prior Res Ctr Hlth Behaviour, Fac Hlth, Callaghan, NSW 2308, Australia
[2] Hunter Med Res Inst, Callaghan, NSW 2308, Australia
[3] Calvary Mater Hosp Newcastle, Haematol Unit, Waratah, NSW 2298, Australia
[4] Univ Newcastle, Sch Med & Publ Hlth, Fac Hlth, Callaghan, NSW 2308, Australia
来源：
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY | 2016年 / 97卷
基金：
澳大利亚国家健康与医学研究理事会; 英国医学研究理事会;
关键词：
Hemato-oncology; Adherence; Compliance; Medication; Hematological cancer; CHRONIC MYELOID-LEUKEMIA; ACUTE LYMPHOBLASTIC-LEUKEMIA; IMATINIB THERAPY; RETROSPECTIVE ANALYSIS; MAINTENANCE THERAPY; ORAL CHEMOTHERAPY; INHIBITOR THERAPY; NONADHERENCE; DASATINIB; NILOTINIB;
D O I：
10.1016/j.critrevonc.2015.08.025
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
To conduct a comprehensive review to examine among hematological cancer patients: (1) rates of adherence to self-administered cancer treatments; and (2) factors impacting on their adherence. Fifty two eligible publications were identified. The majority focused on Chronic Myeloid Leukaemia (CML) (n=40) and Acute Lymphoid Leukaemia (ALL) (n=11) patients. Adherence rates varied and depended on the definition and measures used. Patient understanding about their disease and treatment, and forgetting to take their medication impacted on patients' level of adherence; while the use of reminders reduced forgetfulness. There is a lack of valid and reliable information relating to medication adherence of hematological cancer patients. Based on the limited data available we provide a profile of CML and ALL patients at potential risk of medication non-adherence, as well as a proposed checklist that can be used by health care providers in assessing and supporting patients in adhering to their medication. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：247 / 262
页数：16
相关论文
共 82 条
[1]   Tyrosine Kinase Inhibitors: The First Decade [J].
Agrawal, Meetu ;
Garg, Ravin J. ;
Cortes, Jorge ;
Quintas-Cardama, Alfonso .
CURRENT HEMATOLOGIC MALIGNANCY REPORTS, 2010, 5 (02) :70-80
[2]  
[Anonymous], BLOOD
[3]  
[Anonymous], 2003, Adherence to Long-Term Therapies: Evidence for action
[4]  
[Anonymous], ONCOLOGY
[5]  
[Anonymous], 2013, Critical appraisal skills programme: Making sense of evidence about clinical effectiveness: 11 questions to help you make sense of a trial
[6]  
[Anonymous], HAEMATOLOGICA
[7]  
[Anonymous], ABSTRACT
[8]  
[Anonymous], BLOOD
[9]  
[Anonymous], ASH ANN M
[10]  
[Anonymous], BLOOD
123456789