Antimicrobial resistance (AMR): significance to food quality and safety

被引:36
作者
Nelson, David W. [1 ]
Moore, John E. [2 ,3 ,4 ]
Rao, Juluri R. [1 ,2 ]
机构
[1] AgriFood & Biosci Inst AFBI, Plant Pathol, Newforge Lane, Belfast BT9 5PX, Antrim, North Ireland
[2] Ulster Univ, Sch Biomed Sci, Coleraine, Londonderry, North Ireland
[3] Belfast City Hosp, Northern Ireland Publ Hlth Lab, Dept Bacteriol, Belfast, Antrim, North Ireland
[4] Queens Univ, Ctr Med Expt, Belfast, Antrim, North Ireland
关键词
antibiotic; antimicrobial resistance (AMR); antibiotic paradox; antibiotic discovery void; GROWTH PROMOTERS; ERYTHROMYCIN RESISTANCE; ANTIBIOTIC-RESISTANCE; INFECTIOUS-DISEASES; VANCOMYCIN; MECHANISMS; POULTRY; HISTORY; SPREAD; CRISIS;
D O I
10.1093/fqsafe/fyz003
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Antibiotic resistance presents a significant challenge to clinical, veterinary, and plant health and is now recognized by the World Health Organization (WHO) as a major emerging problem of global significance. As yet, there have been no successful discoveries of classes of novel antibiotics since 1987. There is an antibiotic discovery void, and it is now widely acknowledged that there is an urgent need for the development of novel antimicrobial agents. For economic reasons, many of the largest pharmaceutical companies have abandoned the antibiotic field, and research conducted by academia was scaled back due to funding cuts following the economic crisis. A post-antibiotic era-in which common infections and minor injuries can kill-far from being an apocalyptic fantasy, is indeed a very real possibility for the 21st century.
引用
收藏
页码:15 / 22
页数:8
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