Cannabinoids as therapeutic for PTSD

被引:36
作者
Loflin, Mallory J. E. [1 ]
Babson, Kimberly A. [1 ]
Bonn-Miller, Marcel O. [1 ,2 ,3 ,4 ]
机构
[1] VA Palo Alto Hlth Care Syst, Natl Ctr PTSD, Palo Alto, CA 94304 USA
[2] VA Palo Alto Hlth Care, Ctr Innovat Implementat, Palo Alto, CA USA
[3] Philadelphia VAMC, Ctr Excellence Subst Abuse Treatment & Educ, Philadelphia, PA USA
[4] Univ Penn, Perelman Sch Med, Dept Psychiat, Philadelphia, PA 19104 USA
关键词
POSTTRAUMATIC-STRESS-DISORDER; CONTEXTUAL FEAR MEMORY; POSSIBLE INVOLVEMENT; CANNABIDIOL; SLEEP; EXTINCTION; ANXIETY; 5-HT1A; DELTA(9)-TETRAHYDROCANNABINOL; MODULATION;
D O I
10.1016/j.copsyc.2016.12.001
中图分类号
B84 [心理学];
学科分类号
04 ; 0402 ;
摘要
Limited efficacy for current pharmacotherapy for PTSD indicates that improved pharmacological treatments are needed. Neurobiological research points to cannabinoids as possible therapeutic agents of interest. Moreover, observational reports indicate that there is growing popular interest in therapeutic use of cannabinoids for the alleviation of trauma symptoms. The aim of this review was to present an up-to-date look at current research on the possible therapeutic value of cannabinoids for PTSD. Experimental, preclinical, and clinical findings are discussed.
引用
收藏
页码:78 / 83
页数:6
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