Polymeric N-Halamine Latex Emulsions for Use in Antimicrobial Paints

被引：122

作者：

Cao, Zhengbing ^{[1
]}

Sun, Yuyu ^{[1
]}

机构：

[1] Univ S Dakota, Biomed Engn Program, Sioux Falls, SD 57107 USA

来源：

ACS APPLIED MATERIALS & INTERFACES | 2009年 / 1卷 / 02期

基金：

美国国家科学基金会;

关键词：

polymeric N-halamine; antimicrobal; antibacterial; antifungal; antiviral; antimold; rechargeable; paint; CARE-ASSOCIATED INFECTIONS; NOSOCOMIAL INFECTION; BIOFILM FORMATION; EFFICACY; POLYURETHANE; CELLULOSE; OUTBREAKS; BACTERIA; HALS;

D O I：

10.1021/am800157a

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

A new N halamine monomer, N-chloro-2,2,6,6 tetramethyl-4 piperidinyl methacrylate (CI-TMPM) was synthesized and used to prepare water based polymeric N-halamines by emulsion polymerization. The chemical structures of the samples were characterized with Fourier transform IR C-13 NMR UV/vis and differential scanning calorimetry analyses. Upon the addition of a small amount of the polymeric N halamine latex emulsions into commercial water based latex paints as antimicrobial additives, the new paints provided potent antimicrobial activities against staphylococcus aureus (S aureus. Gram positive bacteria), methicillin resistant S aureus (MRSA; drug-resistant Gram positive bacteria) vancomycin resistant enterococcus (VRE drug resistant Gram positive bacteria). escherichia coh (E coli Gram negative bacteria) Candida tropicahs (C tropicalis fungi) MS2 virus (15597 B virus), and Stachybotrys chartarum spore (S chartarum mold) and they successfully preveted biofilm formation and development. The antimicrobial functions of the new paints were long lasting for more than 1 year under normal in use conditions, easily monitorable by a simple potassium iodine/starch test and readily rechargeable if the functions were accidentally lost as a result of challenging conditions such as heavy soil flooding etc.

引用

页码：494 / 504

页数：11

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