The Development of a Novel Diagnostic Assay That Utilizes a Pseudotyped Vesicular Stomatitis Virus for the Detection of Neutralizing Activity against Crimean-Congo Hemorrhagic Fever Virus

被引：0

作者：

Suda, Yuto ^{[1
,2
]}

Chamberlain, John ^{[3
]}

Dowall, Stuart D. ^{[3
]}

Saijo, Masayuki ^{[2
]}

Horimoto, Taisuke ^{[1
]}

Hewson, Roger ^{[3
]}

Shimojima, Masayuki ^{[2
]}

机构：

[1] Univ Tokyo, Grad Sch Agr & Life Sci, Dept Vet Microbiol, Tokyo, Japan

[2] Natl Inst Infect Dis, Dept Virol 1, Special Pathogens Lab, Gakuen 4-7-1, Tokyo 2080011, Japan

[3] Publ Hlth England, Natl Infect Serv, Porton Down, Wilts, England

来源：

JAPANESE JOURNAL OF INFECTIOUS DISEASES | 2018年 / 71卷 / 03期

基金：

日本学术振兴会;

关键词：

ENZYME-LINKED-IMMUNOSORBENT; IMMUNOGLOBULIN-G ANTIBODIES; RECOMBINANT NUCLEOPROTEIN; DUGBE VIRUS; SERA; PATHOGENESIS; EXPRESSION; IGG;

D O I：

10.7883/yoken.JJID.2017.354

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Crimean-Congo hemorrhagic fever virus is a risk group 4 pathogen, which mandates the use of maximum containment facilities, often termed biosafety level 4 or containment level 4 when working with infectious materials. Diagnostic and research work involving live viruses in such laboratories is timeconsuming and inconvenient, resulting in delays. Herein, we show that serum neutralizing activity against the virus can be measured in low-containment laboratories using a pseudotyped virus.

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收藏

页码：205 / 208

页数：4

相关论文

共 29 条

[1] Pathogenesis of Crimean-Congo Hemorrhagic Fever [J].

Akinci, Esragul ;

Bodur, Hurrem ;

Leblebicioglu, Hakan .

VECTOR-BORNE AND ZOONOTIC DISEASES, 2013, 13 (07) :429-437

[2] Identification and analysis of Crimean-Congo hemorrhagic fever virus from human sera in Tajikistan [J].

Atkinson, Barry ;

Chamberlain, John ;

Jameson, Lisa J. ;

Logue, Christopher H. ;

Lewis, James ;

Belobrova, Evgeniya A. ;

Valikhodzhaeva, Matlyuba ;

Mullojonova, Manija ;

Tishkova, Farida H. ;

Hewson, Roger .

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2013, 17 (11) :E1031-E1037

[3] Crimean-Congo hemorrhagic fever: History, epidemiology, pathogenesis, clinical syndrome and genetic diversity [J].

Bente, Dennis A. ;

Forrester, Naomi L. ;

Watts, Douglas M. ;

McAuley, Alexander J. ;

Whitehouse, Chris A. ;

Bray, Mike .

ANTIVIRAL RESEARCH, 2013, 100 (01) :159-189

[4] Investigation of tick-borne viruses as pathogens of humans in South Africa and evidence of Dugbe virus infection in a patient with prolonged thrombocytopenia [J].

Burt, FJ ;

Spencer, DC ;

Leman, PA ;

Patterson, B ;

Swanepoel, R .

EPIDEMIOLOGY AND INFECTION, 1996, 116 (03) :353-361

[5] ENZYME-LINKED IMMUNOSORBENT ASSAYS FOR THE DETECTION OF ANTIBODY TO CRIMEAN-CONGO HEMORRHAGIC-FEVER VIRUS IN THE SERA OF LIVESTOCK AND WILD VERTEBRATES [J].

BURT, FJ ;

SWANEPOEL, R ;

BRAACK, LEO .

EPIDEMIOLOGY AND INFECTION, 1993, 111 (03) :547-557

[6] A Novel Vaccine against Crimean-Congo Haemorrhagic Fever Protects 100% of Animals against Lethal Challenge in a Mouse Model [J].

Buttigieg, Karen R. ;

Dowall, Stuart D. ;

Findlay-Wilson, Stephen ;

Miloszewska, Aleksandra ;

Rayner, Emma ;

Hewson, Roger ;

Carroll, Miles W. .

PLOS ONE, 2014, 9 (03)

[7] Immunization of Knock-Out α/β Interferon Receptor Mice against High Lethal Dose of Crimean-Congo Hemorrhagic Fever Virus with a Cell Culture Based Vaccine [J].

Canakoglu, Nurettin ;

Berber, Engin ;

Tonbak, Sukru ;

Ertek, Mustafa ;

Sozdutmaz, Ibrahim ;

Aktas, Munir ;

Kalkan, Ahmet ;

Ozdarendeli, Aykut .

PLOS NEGLECTED TROPICAL DISEASES, 2015, 9 (03)

[8] THE NAIROVIRUS GENUS - SEROLOGICAL RELATIONSHIPS [J].

CASALS, J ;

TIGNOR, GH .

INTERVIROLOGY, 1980, 14 (3-4) :144-147

[9] A Virus-Like Particle System Identifies the Endonuclease Domain of Crimean-Congo Hemorrhagic Fever Virus [J].

Devignot, Stephanie ;

Bergeron, Eric ;

Nichol, Stuart ;

Mirazimi, Ali ;

Weber, Friedemann .

JOURNAL OF VIROLOGY, 2015, 89 (11) :5957-5967

[10] Development of an indirect ELISA method for the parallel measurement of IgG and IgM antibodies against Crimean-Congo haemorrhagic fever (CCHF) virus using recombinant nucleoprotein as antigen [J].

Dowall, S. D. ;

Richards, K. S. ;

Graham, V. A. ;

Chamberlain, J. ;

Hewson, R. .

JOURNAL OF VIROLOGICAL METHODS, 2012, 179 (02) :335-341