Synthesis of 3-acylindoles via decarboxylative cross-coupling reaction of free (N-H) indoles with α-oxocarboxylic acids

被引：36

作者：

Gu, Li-Jun ^{[1
]}

Liu, Ji-Yan

Zhang, Li-Zhu

Xiong, Yong

Wang, Rui

机构：

[1] Yunnan Univ Nationalities, State Ethn Affairs Commiss, Key Lab Chem Ethn Med Resources, Kunming 650500, Peoples R China

来源：

CHINESE CHEMICAL LETTERS | 2014年 / 25卷 / 01期

关键词：

3-Acylindoles; Decarboxylative acylation; alpha-Oxocarboxylic acids; ONE-POT; CATALYZED ACYLATION; SUBSTITUTED INDOLES; ARYL BROMIDES; AMINOPHOSPHONATES; STRATEGY;

D O I：

10.1016/j.cclet.2013.10.004

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A convenient and general method for acylation of free (N-H) indoles via palladium-catalyzed decarboxylative cross-coupling reaction was developed. This process provided a useful method for the preparation of diverse 3-acylindoles in high yields utilizing a reaction with readily accessible reactants under mild conditions. (C) 2013 Li-Jun Gu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

引用

页码：90 / 92

页数：3

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