Probiotics and Gut-Brain Axis: promising area in well-being

被引：0

作者：

Gilbert, Kim ^{[1
,2
]}

Gire, Ronan ^{[3
]}

Rousseau, Guy ^{[1
]}

机构：

[1] Hop Sacre Coeur, Ctr Biomed, Montreal, PQ H4J 1C5, Canada

[2] Univ Montreal, Dept Pharmacol, Montreal, PQ H3C 3J7, Canada

[3] Lallemand Hlth Solut, Montreal, PQ H2P 2M6, Canada

来源：

AGRO FOOD INDUSTRY HI-TECH | 2013年 / 24卷 / 04期

关键词：

Gut-brain axis; gut microbiota; probiotics; behaviour; inflammation; TOLL-LIKE RECEPTORS; GERM-FREE; BEHAVIOR; INFECTION; MICE; DYSFUNCTION; MECHANISMS; PATHWAYS; STRESS; MEMORY;

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Intestinal transit is often affected during stressful conditions, suggesting a link between brain and gut. Moreover recent experimental evidence has demonstrated that the gut might also influence the activity of the brain and the behaviour by different mechanisms including nervous transmission, the immune system and the microbiota. Indeed, the gut-brain axis is not only essential for the maintenance of gastrointestinal homeostasis but is also involved in the regulation of cognitive functions and stress. The purpose of this review is to discuss the recent evidence on the gut-brain axis and how modulation of the microbiota using probiotics may be beneficial to our mental and intestinal health.

引用

页码：6 / 9

页数：4

共 30 条

[1]

ABRAMS GD, 1963, LAB INVEST, V12, P355

[2] Prevention of gut leakiness by a probiotic treatment leads to attenuated HPA response to an acute psychological stress in rats [J].

Ait-Belgnaoui, Afifa ;

Durand, Henri ;

Cartier, Christel ;

Chaumaz, Gilles ;

Eutamene, Helene ;

Ferrier, Laurent ;

Houdeau, Eric ;

Fioramonti, Jean ;

Bueno, Lionel ;

Theodorou, Vassilia .

PSYCHONEUROENDOCRINOLOGY, 2012, 37 (11) :1885-1895

[3] The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication [J].

Bercik, P. ;

Park, A. J. ;

Sinclair, D. ;

Khoshdel, A. ;

Lu, J. ;

Huang, X. ;

Deng, Y. ;

Blennerhassett, P. A. ;

Fahnestock, M. ;

Moine, D. ;

Berger, B. ;

Huizinga, J. D. ;

Kunze, W. ;

McLean, P. G. ;

Bergonzelli, G. E. ;

Collins, S. M. ;

Verdu, E. F. .

NEUROGASTROENTEROLOGY AND MOTILITY, 2011, 23 (12) :1132-E544

[4] The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice [J].

Bercik, Premysl ;

Denou, Emmanuel ;

Collins, Josh ;

Jackson, Wendy ;

Lu, Jun ;

Jury, Jennifer ;

Deng, Yikang ;

Blennerhassett, Patricia ;

Macri, Joseph ;

McCoy, Kathy D. ;

Verdu, Elena F. ;

Collins, Stephen M. .

GASTROENTEROLOGY, 2011, 141 (02) :599-U701

[5] The indigenous gastrointestinal microflora [J].

Berg, RD .

TRENDS IN MICROBIOLOGY, 1996, 4 (11) :430-435

[6] Brain-gut interactions [J].

Bonaz, B. .

REVUE DE MEDECINE INTERNE, 2010, 31 (08) :581-585

[7] Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve [J].

Bravo, Javier A. ;

Forsythe, Paul ;

Chew, Marianne V. ;

Escaravage, Emily ;

Savignac, Helene M. ;

Dinan, Timothy G. ;

Bienenstock, John ;

Cryan, John F. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (38) :16050-16055

[8] Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C [J].

Cario, E ;

Gerken, G ;

Podolsky, DK .

GASTROENTEROLOGY, 2004, 127 (01) :224-238

[9] Phenotypic changes in colonocytes following acute stress or activation of mast cells in mice: implications for delayed epithelial barrier dysfunction [J].

Demaude, J ;

Salvador-Cartier, C ;

Fioramonti, J ;

Ferrier, L ;

Bueno, L .

GUT, 2006, 55 (05) :655-661

[10] Bacterial infection causes stress-induced memory dysfunction in mice [J].

Gareau, Melanie G. ;

Wine, Eytan ;

Rodrigues, David M. ;

Cho, Joon Ho ;

Whary, Mark T. ;

Philpott, Dana J. ;

MacQueen, Glenda ;

Sherman, Philip M. .

GUT, 2011, 60 (03) :307-317

← 1 2 3 →