From Single-Core Nanoparticles in Ferrofluids to Multi-Core Magnetic Nanocomposites: Assembly Strategies, Structure, and Magnetic Behavior

被引：28
作者：
Krasia-Christoforou, Theodora [1 ]
Socoliuc, Vlad [2 ]
Knudsen, Kenneth D. [3 ]
Tombacz, Etelka [4 ]
Turcu, Rodica [5 ]
Vekas, Ladislau [2 ]
机构：
[1] Univ Cyprus, Dept Mech & Mfg Engn, 75 Kallipoleos Ave,POB 20537, CY-1678 Nicosia, Cyprus
[2] Romanian Acad, Timisoara Branch, Ctr Fundamental & Adv Tech Res, Lab Magnet Fluids, Mihai Viteazul Ave 24, Timisoara 300223, Romania
[3] Inst Energy Technol IFE, Dept Neutron Mat Characterizat, N-2027 Kjeller, Norway
[4] Univ Pannonia, Soos Erno Water Technol Res & Dev Ctr, Zrinyi M Str 18, H-8800 Nagykanizsa, Hungary
[5] Natl Inst Res & Dev Isotop & Mol Technol, Dept Phys Nanostruct Syst, Donat Str 67-103, Cluj Napoca 400293, Romania
来源：
NANOMATERIALS | 2020年 / 10卷 / 11期
关键词：
magnetic nanoparticle systems; ferrofluids; magnetic fluids; single core; multi-core; clusters; synthesis; functional coating; physical-chemical properties; structural characterization; magnetic characterization; small-angle scattering techniques; nanomedicine; biotechnology; IRON-OXIDE NANOPARTICLES; DRUG-DELIVERY; PHYSICOCHEMICAL CHARACTERIZATION; SUPERPARAMAGNETIC NANOPARTICLES; BIOMEDICAL APPLICATIONS; COLLOIDAL PARTICLES; RELEASE PROPERTIES; RECENT PROGRESS; POLYMER; CLUSTERS;
D O I：
10.3390/nano10112178
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Iron oxide nanoparticles are the basic components of the most promising magnetoresponsive nanoparticle systems for medical (diagnosis and therapy) and bio-related applications. Multi-core iron oxide nanoparticles with a high magnetic moment and well-defined size, shape, and functional coating are designed to fulfill the specific requirements of various biomedical applications, such as contrast agents, heating mediators, drug targeting, or magnetic bioseparation. This review article summarizes recent results in manufacturing multi-core magnetic nanoparticle (MNP) systems emphasizing the synthesis procedures, starting from ferrofluids (with single-core MNPs) as primary materials in various assembly methods to obtain multi-core magnetic particles. The synthesis and functionalization will be followed by the results of advanced physicochemical, structural, and magnetic characterization of multi-core particles, as well as single- and multi-core particle size distribution, morphology, internal structure, agglomerate formation processes, and constant and variable field magnetic properties. The review provides a comprehensive insight into the controlled synthesis and advanced structural and magnetic characterization of multi-core magnetic composites envisaged for nanomedicine and biotechnology.
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页码：1 / 67
页数：67
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