The Verigene dilemma: gram-negative polymicrobial bloodstream infections and clinical decision making

被引：24

作者：

Claeys, Kimberly C. ^{[1
]}

Heil, Emily L. ^{[1
]}

Pogue, Jason M. ^{[2
]}

Lephart, Paul R. ^{[3
]}

Johnson, J. Kristie ^{[4
]}

机构：

[1] Univ Maryland, Sch Pharm, Pharm Practice & Sci, Baltimore, MD 21201 USA

[2] Detroit Med Ctr, Pharm Practice, Detroit, MI USA

[3] Detroit Med Ctr, Microbiol, Detroit, MI USA

[4] Univ Maryland, Sch Med, Pathol, Baltimore, MD 21201 USA

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2018年 / 91卷 / 02期

关键词：

Bloodstream infection; Gram-negative; Microarray; Polymicrobial; Rapid diagnostics; ANTIMICROBIAL STEWARDSHIP; BACTERIA; ASSAY; CULTURES; IMPACT;

D O I：

10.1016/j.diagmicrobio.2018.01.012

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Verigene Blood-Culture Gram-Negative (GN) results in rapid identification of key GNs in bloodstream infections. Its use clinically is limited by low sensitivity in polymicrobial GN infections and concerns for inappropriate antibiotic modification. In a retrospective review of 1003 blood culture sets, the incidence of missed GNs was infrequent, <4%, with the potential to negatively impact the management of GN BSIs in <2% of cases. (C) 2018 Elsevier Inc. All rights reserved.

引用

页码：144 / 146

页数：3

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