A mild and efficient acetylation of alcohols, phenols and amines with acetic anhydride using La(NO3)3•6H2O as a catalyst under solvent-free conditions

被引：90

作者：

Reddy, T. Srikanth ^{[1
]}

Narasimhulu, M. ^{[1
]}

Suryakiran, N. ^{[1
]}

Mahesh, K. Chinni ^{[1
]}

Ashalatha, K. ^{[1
]}

Venkateswarlu, Y. ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Nat Prod Lab, Organ Chem Div 1, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 38期

关键词：

lanthanum(III) nitrate hexahydrate; alcohols; phenols; amines; acetylation; solvent-free conditions;

D O I：

10.1016/j.tetlet.2006.07.059

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A wide variety of alcohols, phenols and amines are efficiently and selectively converted into the corresponding acetates by treatment with acetic anhydride in the presence of catalytic amounts of La(NO3)(3)center dot 6H(2)O under solvent-free conditions at room temperature. The method is compatible with acid sensitive hydroxyl protecting groups such as TBDMS, THP, OBz, OBn, Boc and some isopropylidenes and offers excellent yields of the mono acetates of 1,3-, 1,4- and 1,5-diols. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：6825 / 6829

页数：5

共 23 条

[1] Scandium(III) or lanthanide(III) triflates as recyclable catalysts for the direct acetylation of alcohols with acetic acid [J].