Bioactive constituents from the leaves of Croton tiglium

被引：4
作者：
Jiang, Zhi-Yong [1 ,2 ,3 ,4 ]
Duan, Li-Kun [2 ,3 ]
Feng, Jin-E [2 ,3 ]
Liu, Chun-Jiang [1 ]
Li, Xiao-Fei [1 ]
Li, Yuan [1 ]
Huang, Chun-Qiu [5 ]
Shi, Sheng-Li [6 ]
Zuo, Ai-Xue [1 ]
He, Hong-Ping [1 ]
机构：
[1] Yunnan Univ Chinese Med, Sch Ethn Med, Kunming 650500, Yunnan, Peoples R China
[2] Yunnan Minzu Univ, Key Lab Chem Ethn Med Resources, State Ethn Affairs Commiss, Kunming 650500, Yunnan, Peoples R China
[3] Yunnan Minzu Univ, Minist Educ, Kunming 650500, Yunnan, Peoples R China
[4] Yunnan Univ Chinese Med, Key Lab Modern Res Ethn Med Coll Yunnan Prov, Kunming 650500, Yunnan, Peoples R China
[5] Yunnan Phytopharmaceut Co Ltd, Kunming 650505, Yunnan, Peoples R China
[6] Yuxi Normal Univ, Sch Chem Biol & Environm, Yuxi 653100, Yunnan, Peoples R China
来源：
PHYTOCHEMISTRY LETTERS | 2022年 / 49卷
基金：
中国国家自然科学基金;
关键词：
Croton tiglium; Phorbol esters; Sesquiterpenoids; Larvicidal activity; a-glucosidase inhibitory activity; CYTOTOXIC PHORBOL ESTERS; DITERPENOIDS; SEEDS; SESQUITERPENES;
D O I：
10.1016/j.phytol.2022.03.003
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Fifteen compounds, including five new phorbol esters (1-5) and ten known metabolites were isolated from the leaves of Croton tiglium. The structures of new compounds 1-5 were determined by comprehensive analysis of the HRESIMS, IR, 1D and 2D NMR spectral data. The isolates were assayed for their larvicidal and alpha-glucosidase inhibitory activity; results suggested the new compounds 1-4 possessed significant insecticidal activity, inhibiting the Plutella xylostella with LC50 values ranging from 0.081 to 0.114 mu g/mL, while the sesquiterpenoids 11 and 15 showed noticeable alpha-glucosidase inhibitory activity with IC50 values of 11.27 and 8.13 mu M, respectively.
引用
收藏
页码：65 / 72
页数：8
相关论文
共 50 条
  • [31] Three new diterpenoids from the twigs and leaves of Croton laui
    Yang, Chengmin
    Chen, Huiqin
    Gao, Shuyi
    Wang, Hao
    He, Di
    Cai, Caihong
    Mei, Wenli
    Liu, Shoubai
    Dai, Haofu
    PHYTOCHEMISTRY LETTERS, 2023, 53 : 37 - 41
  • [32] Discovery of a novel protein kinase C activator from Croton tiglium for inhibition of non-small cell lung cancer
    Wang Yuwei
    Tang Chunping
    Yao Sheng
    Lai Huanling
    Li Runze
    Xu Jiahui
    Wang Qianqian
    Fan Xing Xing
    Wu Qi Biao
    Lai-Han, Leung Elaine
    Ye Yang
    Yao Xiaojun
    PHYTOMEDICINE, 2019, 65
  • [33] Bioactive constituents from the rhizomes of Curcuma zedoaria
    Chen, J. J.
    Tsai, T. H.
    Chen, K. S.
    Liao, H. R.
    PLANTA MEDICA, 2014, 80 (16) : 1540 - 1540
  • [34] Bioactive Constituents from the Bryophyta Hypnum plumaeforme
    Li, Jian-Lin
    Wie, Lai-Lai
    Chen, Chen
    Liu, Di
    Gu, Yu-Qin
    Duan-Mu, Jia-Xin
    Chen, Guang-Tong
    Song, Yan
    CHEMISTRY & BIODIVERSITY, 2020, 17 (12)
  • [35] Bioactive constituents from the rhizomes of Atractylodes macrocephala
    Zhang, Haixin
    Lin, Chunyu
    Yin, Luying
    Si, Jinguang
    Yu, Meng
    Li, Jingrong
    Li, Lingyu
    Zhang, Tao
    Zou, Zhongmei
    FITOTERAPIA, 2023, 165
  • [36] Comparative long-term efficacy of phenol-croton oil chemical peels for persistent melasma at varied Croton tiglium oil concentrations
    Maymone, Mayra B. C.
    Mirza, Fatima N.
    Steiner, Denise
    Ribeiro, Felipe
    Landau, Marina
    Marcon, Carolina
    Celidonio, Tereza C.
    Soon, Seaver L.
    Wambier, Carlos G.
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2024, 91 (02) : 336 - 338
  • [37] Highly oxygenated clerodane furanoditerpenoids from the leaves and twigs of Croton yunnanensis
    Wang, Didi
    Mei, Fang
    Nie, Jinchun
    Li, Zhenwei
    Zhang, Daidi
    Guo, Dean
    Li, Wei
    CHINESE JOURNAL OF NATURAL MEDICINES, 2024, 22 (10) : 945 - 954
  • [38] Crotonianoids A-C, Three Unusual Tigliane Diterpenoids from the Seeds of Croton tiglium and Their Anti-Prostate Cancer Activity
    Hu, Rong
    Huang, Jia-Luo
    Yuan, Fang-Yu
    Wei, Xun
    Zou, Ming-Feng
    Tang, Gui-Hua
    Li, Wei
    Yin, Sheng
    JOURNAL OF ORGANIC CHEMISTRY, 2022, 87 (14) : 9301 - 9306
  • [39] Evaluation of developmental toxicity and genotoxicity of aqueous seed extract of Croton tiglium L. using zebrafish
    Yumnamcha, Thangal
    Devi, Maibam Damayanti
    Roy, Debasish
    Nongthomba, Upendra
    DRUG AND CHEMICAL TOXICOLOGY, 2022, 45 (01) : 398 - 406
  • [40] Terpenoid constituents from leaves of Guarea kunthiana
    Garcez, FR
    Garcez, WS
    da Silva, AFG
    Bazzo, RD
    Resende, UM
    JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 2004, 15 (05) : 767 - 772
12345