Melting gel techniques in single nucleotide polymorphism and mutation detection: From theory to automation

被引:0
作者
Bjorheim, J [1 ]
Gaudernack, G [1 ]
Ekstrom, PO [1 ]
机构
[1] Norwegian Radium Hosp, Inst Canc Res, Dept Immunol, Sect Immunotherapy, N-0310 Oslo, Norway
来源
JOURNAL OF SEPARATION SCIENCE | 2002年 / 25卷 / 10-11期
关键词
review; melting gel techniques; denaturant gradient gel electrophoresis; constant denaturant gel electrophoresis; temporal temperature gel electrophoresis; temperature gradient gel electrophoresis; constant denaturant capillary electrophoresis; mutation; single nucleotide polymorphism;
D O I
10.1002/1615-9314(20020701)25:10/11<637::AID-JSSC637>3.0.CO;2-L
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
During the last 20 years several applications and variations of the melting gel techniques have been used for mutation and single nucleotide polymorphism analysis. All melting gel techniques are based on the same theoretical platform and are used by large groups in the research community. This review reports on current methods and applications in the field of melting gel techniques.
引用
收藏
页码:637 / 647
页数:11
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