Utility of Fibroscan® in the evaluation of liver fibrosis

被引：8
作者：
Carrion, Jose A. [1 ]
机构：
[1] Hosp Clin Barcelona, CIBERehd, IDIBAPS, Barcelona, Spain
来源：
GASTROENTEROLOGIA Y HEPATOLOGIA | 2009年 / 32卷 / 06期
关键词：
Elastography; Fibroscan; Non-invasive; Liver fibrosis; TRANSIENT ELASTOGRAPHY FIBROSCAN; HEPATITIS-C RECURRENCE; STIFFNESS MEASUREMENT; PORTAL-HYPERTENSION; NONINVASIVE ASSESSMENT; DIAGNOSIS; CIRRHOSIS; VIRUS; ACCURACY; MARKERS;
D O I：
10.1016/j.gastrohep.2009.01.178
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Chronic Liver diseases produce a progressive accumulation of collagenous fiber in the Liver parenchyma. For years, liver biopsy has been the gold standard to quantify liver fibrosis. Currently, non-invasive alternatives are available to quantify fibrosis. Transient elastography (TE) or Fibroscan (R) quantifies liver rigidity, which is proportional to the grade of liver fibrosis. Studies are available that have evaluated the reliability and limitations of TE in healthy individuals, in patients with acute hepatitis, in distinct chronic liver diseases and in liver transplant recipients. TE is reliable for the diagnosis of liver cirrhosis (F4) and significant fibrosis (F >= 2) but its values may vary according to the patient's characteristics and the etiology of the disease. TE can avoid liver biopsy in 90% of patients with cirrhosis and in up to 70% of those with significant fibrosis when combined with other non-invasive methods. (C) 2008 Elsevier Espana, S.L. All rights reserved.
引用
收藏
页码：415 / 423
页数：9
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