Tungstates: Novel heterogeneous catalysts for the synthesis of 5-substituted 1H-tetrazoles

被引：76

作者：

He, Jinghui ^{[1
]}

Li, Baojun ^{[1
]}

Chen, Fasheng ^{[1
]}

Xu, Zheng ^{[1
]}

Yin, Gui ^{[1
]}

机构：

[1] Nanjing Univ, State Key Lab Coordinat Chem, Sch Chem & Engn, Nanjing 210093, Jiangsu, Peoples R China

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2009年 / 304卷 / 1-2期

关键词：

Tetrazoles; Tungstate; BaWO4; 2+3]-Cycloaddition; Heterogeneous catalyst; TETRAZOLE FORMATION; EFFICIENT SYNTHESIS; NITRILES; AZIDE; CHEMISTRY; SURFACE; OXYGEN;

D O I：

10.1016/j.molcata.2009.01.037

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Most heterogeneous Catalysts utilized for the formation of 5-substituted 1H-tetrazoles contain zinc as the metal core at the catalytically active site. In this paper, we report that the tungstate MWO4 (M = Ba, Ca, Zn, Cd, Cu. Na, H) can catalyze the [2+3] cycloaddition reaction of nitriles with sodium azide to produce 5-substituted 1H-tetrazoles in DMF The catalyst is very efficient, affording good yield of aromatic nitriles and can be reused for several cycles. The mono- and di-addition products from dicyanobenzene can be selectively synthesized, which is a development being reported for the first time. The mechanism of the catalysis may originate from the nitrile group coordinating With the unsaturated W atoms, formed by oxygen vacancies on the surface of solid tungstates. (c) 2009 Elsevier B.V. All rights reserved.

引用

页码：135 / 138

页数：4

共 29 条

[1] TBAF-Catalyzed synthesis of 5-substituted IH-tetrazoles under solventless conditions [J].