Functional yogurt aims to protect against the aflatoxin B1 toxicity in rats

被引：22
作者：
Abdel-Salam, Ahmed M. [1 ]
Badr, Ahmed Noah [2 ]
Zaghloul, Ahmed H. [1 ]
Farrag, Abdel Razik H. [3 ]
机构：
[1] Natl Res Ctr, Dept Dairy Sci, Cairo, Egypt
[2] Natl Res Ctr, Food Toxicol & Contaminants Dept, Cairo 12622, Egypt
[3] Natl Res Ctr, Dept Pathol, Cairo, Egypt
来源：
TOXICOLOGY REPORTS | 2020年 / 7卷
关键词：
Aflatoxin; Chicory-root extract; Functional yogurt; Mycotoxin; Oxidative stress; PROBIOTICS LACTOBACILLUS-RHAMNOSUS; DAIRY-PRODUCTS; BIFIDOBACTERIUM-LACTIS; INULIN; SUPPLEMENTATION; METABOLISM; ASSAY; MILK; B-1; OLIGOSACCHARIDES;
D O I：
10.1016/j.toxrep.2020.10.012
中图分类号：
R99 [毒物学（毒理学）];
学科分类号：
100405 ;
摘要：
Recently, the rise of mycotoxin contamination in food materials was found to be due to several factors, including climatic changes' impact. Therefore, the aim of this study was to provide a novel food product that allows the reduction of aflatoxin impact in animal tissues. Chicory root-extract (CRE) was evaluated for its active components, antioxidant potency, and antimicrobial activity. The CRE was utilized to produce functional yogurt (FY) that was evaluated in-vivo using experimental rats. The CRE showed high antioxidant activity and recorded valuable content of the active components. Results also showed a high antimicrobial effect against toxigenic fungal strains. The results have reflected the efficiency of the FY to suppress aflatoxin impacts in the animal tissues and biochemical parameters of rats-serum. An enhancement was recorded inliver and kidney functions for rats taking FY with the presence of aflatoxin. It was concluded that consumption of the FY assisted in suppression of the oxidative stress in rats-tissues.
引用
收藏
页码：1412 / 1420
页数：9
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