Synchrotron radiation techniques for nanotoxicology

被引：31
作者：
Li, Yu-Feng [1 ,2 ]
Zhao, Jiating [1 ,2 ]
Qu, Ying [3 ]
Gao, Yuxi [1 ,2 ]
Guo, Zhenghang [4 ]
Liu, Zuoliang [4 ]
Zhao, Yuliang [1 ,2 ,3 ]
Chen, Chunying [3 ]
机构：
[1] Chinese Acad Sci, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing, Peoples R China
[2] Chinese Acad Sci, Inst High Energy Phys, Lab Metall & Nanometall, Beijing, Peoples R China
[3] Natl Ctr Nanosci & Technol, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing, Peoples R China
[4] Beijing Natl Day Sch, Beijing, Peoples R China
来源：
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE | 2015年 / 11卷 / 06期
基金：
中国国家自然科学基金;
关键词：
Synchrotron radiation; Nanotoxicology; In vitro; In vivo; Ecotoxicology; WALLED CARBON NANOTUBES; SINGLE-PARTICLE TRACKING; SILVER NANOPARTICLES; GOLD NANOPARTICLES; CELLULAR UPTAKE; TIO2; NANOPARTICLES; OXIDE NANOPARTICLES; IN-VIVO; CAENORHABDITIS-ELEGANS; ANTIBACTERIAL ACTIVITY;
D O I：
10.1016/j.nano.2015.04.008
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Nanotoxicology studies the interactions of engineered nanomaterials with biological systems. Traditional in vitro and in vivo toxicological assays have been successfully employed. However, the toxicological mechanisms of nanoparticles might not be the same as those incurred in traditional molecular toxicology. Furthermore, how to realize in situ and real time measurements especially in the biological microenvironment is still a challenge. Synchrotron radiation, which is highly polarized and tunable, has been proved to play an indispensible role for nanotoxicology studies. In this review, the role of synchrotron radiation techniques is summarized in screening physicochemical characteristics, in vitro and in vivo behaviors, and ecotoxicological effects of engineered nanomaterials. (C) 2015 Elsevier Inc. All rights reserved.
引用
收藏
页码：1531 / 1549
页数：19
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