Regenerated cellulose/β-cyclodextrin scaffold prepared using ionic liquid

被引：23
|
作者：
Soheilmoghaddam, Mohammad [1 ]
Sharifzadeh, Ghorbanali [1 ]
Pour, Raheleh Heidar [1 ]
Wahit, Mat Uzir [2 ]
Whye, Wong Tuck [1 ]
Lee, Xiau Yeen [1 ]
机构：
[1] Univ Teknol Malaysia, Fac Chem Engn, Dept Polymer Engn, Johor Baharu, Malaysia
[2] Univ Teknol Malaysia, Ctr Composites, Skudai 81310, Johor, Malaysia
来源：
MATERIALS LETTERS | 2014年 / 135卷
关键词：
Biomaterials; Porous materials; Composite materials; Regenerated cellulose; beta cyclodextrin; Scaffolds;
D O I：
10.1016/j.matlet.2014.07.169
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Regenerated cellulose/beta-cyclodextrin (RC/beta-CD) tissue engineering scaffolds were fabricated by two particulate leaching techniques using environmental-friendly 1-butyl-3-methylimidazolium chloride (BMIMCI) ionic liquid. In one case, the pore inducing particles were water-soluble (edible salt) and in the other, they were water-insoluble poly (methyl methacrylate) (PMMA). The water-soluble particulate leaching and water-insoluble methods resulted in scaffolds with 70-75% and 91-93% porosity, respectively. X-ray diffraction revealed lower crystallinity of the RC/beta-CD scaffolds as compared to pure RC. The RC/beta-CD scaffolds prepared by water-insoluble leaching method showed the highest water uptake properties. In vitro cytotoxicity test demonstrated that RC/beta-CD scaffolds are cytocompatible. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码：210 / 213
页数：4
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