Histiocytoses: General classification and molecular criteria

被引:5
作者
Emile, Jean-Francois [1 ,2 ]
Charlotte, Frederic [3 ]
Chassagne-Clement, Catherine [4 ]
Copin, Marie-Christine [5 ]
Fraitag, Sylvie [6 ]
Mokhtari, Karima [3 ]
Moreau, Anne [7 ]
机构
[1] Univ Versailles, Univ Paris Saclay, EA4340 Biomarqueurs Cancerol & Onco Hematol 7, F-78035 Versailles, France
[2] Hop Ambroise Pare, AP HP, Serv Pathol, 9,Ave Charles de Gaulle, F-92104 Boulogne, France
[3] Hop La Pitie Salpetriere, AP HP, Serv Pathol, F-75013 Paris, France
[4] Ctr Leon Berard, Serv Pathol, F-69373 Lyon, France
[5] CHU Lille, Serv Pathol, F-59037 Lille, France
[6] Hop Necker Enfants Malad, AP HP, Serv Pathol, F-75015 Paris, France
[7] Hop Ambroise Pare, Serv Pathol, F-44000 Nantes, France
来源
PRESSE MEDICALE | 2017年 / 46卷 / 01期
关键词
LANGERHANS CELL HISTIOCYTOSIS; ROSAI-DORFMAN DISEASE; ERDHEIM-CHESTER DISEASE; FOLLICULAR LYMPHOMAS; HIGH PREVALENCE; BRAF MUTATIONS; SARCOMA; ASSOCIATION; DIAGNOSIS; MAP2K1;
D O I
10.1016/j.lpm.2016.01.016
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Histiocytoses are rare and heterogeneous disease sharing histology, characterized by accumulation of histiocytes. They may be inherited or sporadic, and related to the accumulation of endo-or exogenous material in macrophages or to macrophage activation. Recent discoveries have shown that some histiocytoses, such as Langerhans cell histiocytosis or Erdheim-Chester disease, previously considered as idiopathic or inflammatory were clonal myeloid proliferations. This review presents the general classification of histiocytoses, and describes diagnostic and molecular criteria of idiopathic histiocytoses and histiocytic neoplasms.
引用
收藏
页码:46 / 54
页数:9
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