Cancer cell-targeted nanoprobe for multilayer imaging of diverse biomarkers and precise photodynamic therapy

被引:7
作者
Fu, Zhuolin [1 ]
Wu, Yingdi [1 ]
Ren, Chunnian [2 ]
Song, Weiling [1 ]
Zhang, Xiaoru [1 ]
Yue, Meie [1 ]
Li, Ying [1 ]
机构
[1] Qingdao Univ Sci & Technol, Key Lab Opt Elect Sensing & Analyt Chem Life Sci, Key Lab Analyt Chem Life Sci Univ Shandong, MOE,Shandong Key Lab Biochem Anal,Coll Chem & Mol, Qingdao 266042, Peoples R China
[2] Qingdao Univ Sci & Technol, Coll Informat Sci & Technol, Qingdao 266042, Peoples R China
基金
中国国家自然科学基金;
关键词
QUANTUM DOTS; NANOPARTICLES; APTAMER;
D O I
10.1039/d0cc06305c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel multifunctional nanoprobe was designed for cancer cell targeted multilayer imaging of two cancer biomarkers. Based on the proposed method, in situ imaging of membrane MUC1 mucin and cytoplasmic microRNA miR-21 coupled with precise photodynamic therapy was achieved.
引用
收藏
页码:15208 / 15211
页数:4
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