Topical simvastatin: Preclinical evidence for a treatment of skin inflammatory conditions

被引：23

作者：

Otuki, Michel Fleith ^{[1
]}

Pietrovski, Evelise Fernandes ^{[1
]}

Cabrini, Daniela Almeida ^{[1
]}

机构：

[1] Univ Fed Parana, Dept Farmacol, Setor Ciencias Biol, Ctr Politecn, BR-81530900 Curitiba, Parana, Brazil

来源：

JOURNAL OF DERMATOLOGICAL SCIENCE | 2006年 / 44卷 / 01期

关键词：

statin; simvastatin; skin inflammation;

D O I：

10.1016/j.jdermsci.2006.04.006

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

引用

页码：45 / 47

页数：3

共 10 条

[1] Toward immunomodulatory and anti-inflammatory properties of statins [J].

Arnaud, C ;

Braunersreuther, V ;

Mach, F .

TRENDS IN CARDIOVASCULAR MEDICINE, 2005, 15 (06) :202-206

[2] A novel anti-inflammatory role for simvastatin in inflammatory arthritis [J].

Leung, BP ;

Sattar, N ;

Crilly, A ;

Prach, M ;

McCarey, DW ;

Payne, H ;

Madhok, R ;

Campbell, C ;

Gracie, JA ;

Liew, FY ;

McInnes, IB .

JOURNAL OF IMMUNOLOGY, 2003, 170 (03) :1524-1530

[3] A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma [J].

McKay, A ;

Leung, BP ;

McInnes, IB ;

Thomson, NC ;

Liew, FY .

JOURNAL OF IMMUNOLOGY, 2004, 172 (05) :2903-2908

[4] Statins: novel additions to the dermatologic arsenal? [J].

Namazi, MR .

EXPERIMENTAL DERMATOLOGY, 2004, 13 (06) :337-339

[5] Topical antiinflammatory effects of the ether extract from Protium kleinii and α-amyrin pentacyclic triterpene [J].

Otuki, MF ;

Vieira-Lima, F ;

Malhairos, K ;

Yunes, RA ;

Calixto, JB .

EUROPEAN JOURNAL OF PHARMACOLOGY, 2005, 507 (1-3) :253-259

[6]

PATRICK E, 1987, J INVEST DERMATOL, V88, P24

[7] Role of leukocyte influx in tissue prostaglandin H synthase-2 overexpression induced by phorbol ester and arachidonic acid in skin [J].

Sánchez, T ;

Moreno, JJ .

BIOCHEMICAL PHARMACOLOGY, 1999, 58 (05) :877-879

[8] Characterization of human T cells that regulate neutrophilic skin inflammation [J].

Schaerli, P ;

Britschgi, M ;

Keller, M ;

Steiner, UC ;

Steinmann, LS ;

Moser, B ;

Pichler, WJ .

JOURNAL OF IMMUNOLOGY, 2004, 173 (03) :2151-2158

[9]

Towbin H., 1995, Inflammation Research, V44, pS160, DOI 10.1007/BF01778311

[10] Statins as anti-inflammatory agents [J].

Weitz-Schmidt, G .

TRENDS IN PHARMACOLOGICAL SCIENCES, 2002, 23 (10) :482-486

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