An organized and functional thymus generated from FOXN1-reprogrammed fibroblasts

被引:120
作者
Bredenkamp, Nicholas [1 ]
Ulyanchenko, Svetlana [1 ]
O'Neill, Kathy Emma [1 ]
Manley, Nancy Ruth [2 ]
Vaidya, Harsh Jayesh [1 ]
Blackburn, Catherine Clare [1 ]
机构
[1] Univ Edinburgh, Ctr Regenerat Med, Sch Biol Sci, Inst Stem Cell Res,Med Res Council, Edinburgh EH16 4UU, Midlothian, Scotland
[2] Univ Georgia, Dept Genet, Athens, GA 30602 USA
基金
英国生物技术与生命科学研究理事会; 英国医学研究理事会;
关键词
T-CELL DEVELOPMENT; EMBRYONIC STEM-CELLS; DELTA-LIKE-1; IN-VITRO; EPITHELIAL-CELLS; LINEAGE COMMITMENT; PROGENITOR CELLS; DIFFERENTIATION; INDUCTION; GROWTH; MICROENVIRONMENT;
D O I
10.1038/ncb3023
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
10.1038/ncb3023
引用
收藏
页码:902 / 908
页数:7
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