Evidence-based (S3) Guideline on (anogenital) Lichen sclerosus

被引:196
作者
Kirtschig, G. [1 ,2 ]
Becker, K. [3 ]
Guenthert, A. [4 ]
Jasaitiene, D. [5 ]
Cooper, S. [6 ,7 ]
Chi, C. -C. [8 ,9 ]
Kreuter, A. [10 ]
Rall, K. K. [11 ,12 ]
Aberer, W. [13 ]
Riechardt, S. [14 ]
Casabona, F. [15 ]
Powell, J. [16 ]
Brackenbury, F. [17 ]
Erdmann, R. [18 ]
Lazzeri, M. [19 ]
Barbagli, G. [19 ]
Wojnarowska, F. [20 ]
机构
[1] Univ Nottingham, Ctr Evidence Based Dermatol, Nottingham NG7 2RD, England
[2] Univ Tubingen, Inst Gen Practice & Interprofess Care, Tubingen, Germany
[3] Deutsch Gesell Kinderchirurg, Off Paediat Surg, Bonn, Germany
[4] Cantonal Hosp Lucerne, Deptartment Obstet & Gynecol, Deutsch Gesell Gynakol & Geburtshilfe, Luzern, Switzerland
[5] Republican Hosp Panevezys, Dept Skin & Venereal Dis, Lithuanian Assoc Dermatovenereologists, Panevezys, Lithuania
[6] Oxford Univ Hosp NHS Trust, Dept Dermatol, Oxford, England
[7] Univ Oxford, Oxford, England
[8] Chang Gung Mem Hosp, Dept Dermatol, Chiayi, Taiwan
[9] Chang Gung Univ, Coll Med, Taoyuan, Taiwan
[10] HELIOS St Elisabeth Hosp Oberhausen, Dept Dermatol Venereol & Allergol, Oberhausen, Germany
[11] Univ Tubingen Hosp, Res Ctr, Tubingen, Germany
[12] Univ Tubingen Hosp, Dept Womens Hlth, Tubingen, Germany
[13] Med Univ Graz, Dept Dermatol, Graz, Austria
[14] Univ Hamburg, Dept Urol & Paediat Urol, Deutsch Gesell Urol, Hamburg, Germany
[15] Osped Andrea Gallino, Chirurg Plast Rigenerat, SC Chirurg Plast, Genoa, Italy
[16] Hampshire Hosp Fdn Trust, Dept Dermatol, Winchester, Hants, England
[17] Assoc Lichen Sclerosus & Vulval Hlth, Www Lichensclerosus Org, Oxford, England
[18] Charite, Div Evidence Based Med, Klin Dermatol Venerol & Allergol, Dev Search Strategy & Performance Literature Sear, D-13353 Berlin, Germany
[19] Ctr Chirurg Toscano, Arezzo, Italy
[20] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Clin Med, Oxford OX3 9DU, England
关键词
BALANITIS XEROTICA OBLITERANS; EXTRACELLULAR-MATRIX PROTEIN-1; ET-ATROPHICUS; CLOBETASOL PROPIONATE; FOLLOW-UP; PHOTODYNAMIC THERAPY; BORRELIA-BURGDORFERI; TOPICAL APPLICATION; RISK-FACTORS; PENILE;
D O I
10.1111/jdv.13136
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Lichen sclerosus (LS) is an inflammatory skin disease that usually involves the anogenital area. All patients with symptoms or signs suspicious of lichen sclerosus should be seen at least once initially by a physician with a special interest in the disease in order to avoid delay in diagnosis, as early treatment may cure the disease in some and reduce or prevent scarring. The diagnosis is made clinically in most cases. Biopsies should only be performed under certain circumstances. The gold standard for treatment remains potent to very potent topical steroids; however, mild and moderate disease in boys and men may be cured by circumcision. Certain triggers should be avoided. http://www.euroderm.org/images/stories/guidelines/2014/S3-Guideline-on-Lichen-sclerosus.pdf http://www.awmf.org/fachgesellschaften/mitgliedsgesellschaften/visitenkarte/fg/deutsche-gesellschaft-fuer-gynaekologie-und-geburtshilfe-dggg.html.
引用
收藏
页码:E1 / E43
页数:43
相关论文
共 170 条
  • [71] Photodynamic therapy of vulvar lichen sclerosus with 5-aminolevulinic acid
    Hillemanns, P
    Untch, M
    Pröve, F
    Baumgartner, R
    Hillemanns, M
    Korell, M
    [J]. OBSTETRICS AND GYNECOLOGY, 1999, 93 (01) : 71 - 74
  • [72] An immunohistochemical study of androgen, oestrogen and progesterone receptors in the vulva and vagina
    Hodgins, MB
    Spike, RC
    Mackie, RM
    MacLean, AB
    [J]. BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1998, 105 (02): : 216 - 222
  • [73] Lichen sclerosus in men is associated with elevated body mass index, diabetes mellitus, coronary artery disease and smoking
    Hofer, Matthias D.
    Meeks, Joshua J.
    Mehdiratta, Nitin
    Granieri, Michael A.
    Cashy, John
    Gonzalez, Chris M.
    [J]. WORLD JOURNAL OF UROLOGY, 2014, 32 (01) : 105 - 108
  • [74] Howard Anne, 2004, Australas J Dermatol, V45, P12, DOI 10.1111/j.1440-0960.2004.00026.x
  • [75] Jensen LS, 2012, DAN MED J, V59
  • [76] JORGENSEN ET, 1993, ACTA DERM-VENEREOL, V73, P55
  • [77] Decrease in epidermal CD44 expression as a potential mechanism for abnormal hyaluronate accumulation in superficial dermis in lichen sclerosus et atrophicus
    Kaya, G
    Augsburger, E
    Stamenkovic, I
    Saurat, JH
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2000, 115 (06) : 1054 - 1058
  • [78] Selective suppression of CD44 in keratinocytes of mice bearing an antisense CD44 transgene driven by a tissue-specific promoter disrupts hyaluronate metabolism in the skin and impairs keratinocyte proliferation
    Kaya, G
    Rodriguez, I
    Jorcano, JL
    Vassalli, P
    Stamenkovic, I
    [J]. GENES & DEVELOPMENT, 1997, 11 (08) : 996 - 1007
  • [79] Kirtschig G., 2014, J WOMENS HLTH CARE, V3, P209
  • [80] Balanitis xerotica obliterans: Epidemiologic distribution in an equal access health care system
    Kizer, WS
    Prarie, T
    Morey, AF
    [J]. SOUTHERN MEDICAL JOURNAL, 2003, 96 (01) : 9 - 11