Evidence-based (S3) Guideline on (anogenital) Lichen sclerosus

被引:196
作者
Kirtschig, G. [1 ,2 ]
Becker, K. [3 ]
Guenthert, A. [4 ]
Jasaitiene, D. [5 ]
Cooper, S. [6 ,7 ]
Chi, C. -C. [8 ,9 ]
Kreuter, A. [10 ]
Rall, K. K. [11 ,12 ]
Aberer, W. [13 ]
Riechardt, S. [14 ]
Casabona, F. [15 ]
Powell, J. [16 ]
Brackenbury, F. [17 ]
Erdmann, R. [18 ]
Lazzeri, M. [19 ]
Barbagli, G. [19 ]
Wojnarowska, F. [20 ]
机构
[1] Univ Nottingham, Ctr Evidence Based Dermatol, Nottingham NG7 2RD, England
[2] Univ Tubingen, Inst Gen Practice & Interprofess Care, Tubingen, Germany
[3] Deutsch Gesell Kinderchirurg, Off Paediat Surg, Bonn, Germany
[4] Cantonal Hosp Lucerne, Deptartment Obstet & Gynecol, Deutsch Gesell Gynakol & Geburtshilfe, Luzern, Switzerland
[5] Republican Hosp Panevezys, Dept Skin & Venereal Dis, Lithuanian Assoc Dermatovenereologists, Panevezys, Lithuania
[6] Oxford Univ Hosp NHS Trust, Dept Dermatol, Oxford, England
[7] Univ Oxford, Oxford, England
[8] Chang Gung Mem Hosp, Dept Dermatol, Chiayi, Taiwan
[9] Chang Gung Univ, Coll Med, Taoyuan, Taiwan
[10] HELIOS St Elisabeth Hosp Oberhausen, Dept Dermatol Venereol & Allergol, Oberhausen, Germany
[11] Univ Tubingen Hosp, Res Ctr, Tubingen, Germany
[12] Univ Tubingen Hosp, Dept Womens Hlth, Tubingen, Germany
[13] Med Univ Graz, Dept Dermatol, Graz, Austria
[14] Univ Hamburg, Dept Urol & Paediat Urol, Deutsch Gesell Urol, Hamburg, Germany
[15] Osped Andrea Gallino, Chirurg Plast Rigenerat, SC Chirurg Plast, Genoa, Italy
[16] Hampshire Hosp Fdn Trust, Dept Dermatol, Winchester, Hants, England
[17] Assoc Lichen Sclerosus & Vulval Hlth, Www Lichensclerosus Org, Oxford, England
[18] Charite, Div Evidence Based Med, Klin Dermatol Venerol & Allergol, Dev Search Strategy & Performance Literature Sear, D-13353 Berlin, Germany
[19] Ctr Chirurg Toscano, Arezzo, Italy
[20] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Clin Med, Oxford OX3 9DU, England
关键词
BALANITIS XEROTICA OBLITERANS; EXTRACELLULAR-MATRIX PROTEIN-1; ET-ATROPHICUS; CLOBETASOL PROPIONATE; FOLLOW-UP; PHOTODYNAMIC THERAPY; BORRELIA-BURGDORFERI; TOPICAL APPLICATION; RISK-FACTORS; PENILE;
D O I
10.1111/jdv.13136
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Lichen sclerosus (LS) is an inflammatory skin disease that usually involves the anogenital area. All patients with symptoms or signs suspicious of lichen sclerosus should be seen at least once initially by a physician with a special interest in the disease in order to avoid delay in diagnosis, as early treatment may cure the disease in some and reduce or prevent scarring. The diagnosis is made clinically in most cases. Biopsies should only be performed under certain circumstances. The gold standard for treatment remains potent to very potent topical steroids; however, mild and moderate disease in boys and men may be cured by circumcision. Certain triggers should be avoided. http://www.euroderm.org/images/stories/guidelines/2014/S3-Guideline-on-Lichen-sclerosus.pdf http://www.awmf.org/fachgesellschaften/mitgliedsgesellschaften/visitenkarte/fg/deutsche-gesellschaft-fuer-gynaekologie-und-geburtshilfe-dggg.html.
引用
收藏
页码:E1 / E43
页数:43
相关论文
共 170 条
  • [61] LICHEN SCLEROSUS ET ATROPHICUS - A STUDY OF 76 CASES AND THEIR RELATION TO DIABETES
    GARCIABRAVO, B
    SANCHEZPEDRENO, P
    RODRIGUEZPICHARDO, A
    CAMACHO, F
    [J]. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1988, 19 (03) : 482 - 485
  • [62] Goldstein AT, 2005, J REPROD MED, V50, P477
  • [63] Green C, 2013, MENOPAUSE INT
  • [64] Early onset vulvar Lichen sclerosus in premenopausal women and oral contraceptives
    Guenthert, Andreas R.
    Faber, Melanie
    Knappe, Gabriele
    Hellriegel, Simin
    Emons, Guenter
    [J]. EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2008, 137 (01) : 56 - 60
  • [65] Differential gene hypermethylation in genital lichen sclerosus and cancer: a comparative study
    Guerrero-Setas, David
    Perez-Janices, Noemi
    Ojer, Amaya
    Blanco-Fernandez, Laura
    Guarch-Troyas, Carmen
    Guarch, Rosa
    [J]. HISTOPATHOLOGY, 2013, 63 (05) : 659 - 669
  • [66] Lichen sclerosus: Role of occlusion of the genital skin in the pathogenesis
    Gupta, Somesh
    Malhotra, Amit Kumar
    Ajith, C.
    [J]. INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY, 2010, 76 (01) : 56 - 58
  • [67] AN INVESTIGATION INTO THE INCIDENCE OF AUTOIMMUNE DISORDERS IN PATIENTS WITH LICHEN SCLEROSUS AND ATROPHICUS
    HARRINGTON, CI
    DUNSMORE, IR
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 1981, 104 (05) : 563 - 566
  • [68] Multicentre, phase II trial on the safety and efficacy of topical tacrolimus ointment for the treatment of lichen sclerosus
    Hengge, U. R.
    Krause, W.
    Hofmann, H.
    Stadler, R.
    Gross, G.
    Meurer, M.
    Brinkmeier, T.
    Frosch, P.
    Moll, I.
    Fritsch, P.
    Mueller, K.
    Meykadeh, N.
    Marini, A.
    Ruzicka, T.
    Gollnick, H.
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 2006, 155 (05) : 1021 - 1028
  • [69] A population-based case-control study of aetiological factors associated with vulval lichen sclerosus
    Higgins, C. A.
    Cruickshank, M. E.
    [J]. JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2012, 32 (03) : 271 - 275
  • [70] Higgins J., 2008, COCHRANE COLLABORATI, DOI [DOI 10.1002/9780470712184.CH8, 10.1002/9780470712184.ch5]