Evidence-based (S3) Guideline on (anogenital) Lichen sclerosus

被引：196

作者：

Kirtschig, G. ^{[1
,2
]}

Becker, K. ^{[3
]}

Guenthert, A. ^{[4
]}

Jasaitiene, D. ^{[5
]}

Cooper, S. ^{[6
,7
]}

Chi, C. -C. ^{[8
,9
]}

Kreuter, A. ^{[10
]}

Rall, K. K. ^{[11
,12
]}

Aberer, W. ^{[13
]}

Riechardt, S. ^{[14
]}

Casabona, F. ^{[15
]}

Powell, J. ^{[16
]}

Brackenbury, F. ^{[17
]}

Erdmann, R. ^{[18
]}

Lazzeri, M. ^{[19
]}

Barbagli, G. ^{[19
]}

Wojnarowska, F. ^{[20
]}

机构：

[1] Univ Nottingham, Ctr Evidence Based Dermatol, Nottingham NG7 2RD, England

[2] Univ Tubingen, Inst Gen Practice & Interprofess Care, Tubingen, Germany

[3] Deutsch Gesell Kinderchirurg, Off Paediat Surg, Bonn, Germany

[4] Cantonal Hosp Lucerne, Deptartment Obstet & Gynecol, Deutsch Gesell Gynakol & Geburtshilfe, Luzern, Switzerland

[5] Republican Hosp Panevezys, Dept Skin & Venereal Dis, Lithuanian Assoc Dermatovenereologists, Panevezys, Lithuania

[6] Oxford Univ Hosp NHS Trust, Dept Dermatol, Oxford, England

[7] Univ Oxford, Oxford, England

[8] Chang Gung Mem Hosp, Dept Dermatol, Chiayi, Taiwan

[9] Chang Gung Univ, Coll Med, Taoyuan, Taiwan

[10] HELIOS St Elisabeth Hosp Oberhausen, Dept Dermatol Venereol & Allergol, Oberhausen, Germany

[11] Univ Tubingen Hosp, Res Ctr, Tubingen, Germany

[12] Univ Tubingen Hosp, Dept Womens Hlth, Tubingen, Germany

[13] Med Univ Graz, Dept Dermatol, Graz, Austria

[14] Univ Hamburg, Dept Urol & Paediat Urol, Deutsch Gesell Urol, Hamburg, Germany

[15] Osped Andrea Gallino, Chirurg Plast Rigenerat, SC Chirurg Plast, Genoa, Italy

[16] Hampshire Hosp Fdn Trust, Dept Dermatol, Winchester, Hants, England

[17] Assoc Lichen Sclerosus & Vulval Hlth, Www Lichensclerosus Org, Oxford, England

[18] Charite, Div Evidence Based Med, Klin Dermatol Venerol & Allergol, Dev Search Strategy & Performance Literature Sear, D-13353 Berlin, Germany

[19] Ctr Chirurg Toscano, Arezzo, Italy

[20] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Clin Med, Oxford OX3 9DU, England

来源：

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY | 2015年 / 29卷 / 10期

关键词：

BALANITIS XEROTICA OBLITERANS; EXTRACELLULAR-MATRIX PROTEIN-1; ET-ATROPHICUS; CLOBETASOL PROPIONATE; FOLLOW-UP; PHOTODYNAMIC THERAPY; BORRELIA-BURGDORFERI; TOPICAL APPLICATION; RISK-FACTORS; PENILE;

D O I：

10.1111/jdv.13136

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Lichen sclerosus (LS) is an inflammatory skin disease that usually involves the anogenital area. All patients with symptoms or signs suspicious of lichen sclerosus should be seen at least once initially by a physician with a special interest in the disease in order to avoid delay in diagnosis, as early treatment may cure the disease in some and reduce or prevent scarring. The diagnosis is made clinically in most cases. Biopsies should only be performed under certain circumstances. The gold standard for treatment remains potent to very potent topical steroids; however, mild and moderate disease in boys and men may be cured by circumcision. Certain triggers should be avoided. http://www.euroderm.org/images/stories/guidelines/2014/S3-Guideline-on-Lichen-sclerosus.pdf http://www.awmf.org/fachgesellschaften/mitgliedsgesellschaften/visitenkarte/fg/deutsche-gesellschaft-fuer-gynaekologie-und-geburtshilfe-dggg.html.

引用

页码：E1 / E43

页数：43

共 170 条

[51] TREATMENT OF PSORIASIS AND ATOPIC-DERMATITIS WITH HALCINONIDE CREAM APPLIED ONCE AND 3 TIMES DAILY
FREDRIKSSON, T
LASSUS, A
BLEEKER, J
[J]. BRITISH JOURNAL OF DERMATOLOGY, 1980, 102 (05) : 575 - 577
[52] FRIEDRICH EG, 1971, OBSTET GYNECOL, V37, P677
[53] SERUM LEVELS OF SEX-HORMONES IN VULVAR LICHEN SCLEROSUS, AND THE EFFECT OF TOPICAL TESTOSTERONE
FRIEDRICH, EG
KALRA, PS
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1984, 310 (08) : 488 - 491
[54] Funaro Deana, 2004, Dermatol Ther, V17, P28, DOI 10.1111/j.1396-0296.2004.04004.x
[55] Light microscopic criteria for the diagnosis of early vulvar lichen sclerosus - A comparison with lichen planus
Fung, MA
LeBoit, PE
[J]. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1998, 22 (04) : 473 - 478
[56] Incidence of penile Lichen sclerosus
Fung, MA
LeBoit, PE
[J]. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2001, 44 (05) : 878 - 879
[57] Altered global methylation and hydroxymethylation status in vulvar lichen sclerosus: further support for epigenetic mechanisms
Gambichler, T.
Terras, S.
Kreuter, A.
Skrygan, M.
[J]. BRITISH JOURNAL OF DERMATOLOGY, 2014, 170 (03) : 687 - 693
[58] Differential expression of connective tissue growth factor and extracellular matrix proteins in lichen sclerosus
Gambichler, T.
Skrygan, M.
Czempiel, V.
Tigges, C.
Kobus, S.
Meier, J. J.
Koehler, C. U.
Scola, N.
Stuecker, M.
Altmeyer, P.
Kreuter, A.
[J]. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2012, 26 (02) : 207 - 212
[59] Significant upregulation of antimicrobial peptides and proteins in lichen sclerosus
Gambichler, T.
Skrygan, M.
Tigges, C.
Kobus, S.
Glaeser, R.
Kreuter, A.
[J]. BRITISH JOURNAL OF DERMATOLOGY, 2009, 161 (05) : 1136 - 1142
[60] The association between HLA DR, DQ antigens, and vulval lichen sclerosus in the UK: HLA DRB1*12 and its associated DRB1*12/DQB1*0301/04/091010 haplotype confers susceptibility to vulval lichen sclerosus, and HLA DRB1*0301104 and its associated DRB1*0301/04/DQB1*0201/02/03 haplotype protects from vulval lichen sclerosus
Gao, XH
Barnardo, MCMN
Winsey, S
Ahmad, T
Cook, J
Agudelo, JD
Zhai, N
Powell, JJ
Fuggle, SV
Wojnarowska, F
[J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2005, 125 (05) : 895 - 899

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