Evidence-based (S3) Guideline on (anogenital) Lichen sclerosus

被引:207
作者
Kirtschig, G. [1 ,2 ]
Becker, K. [3 ]
Guenthert, A. [4 ]
Jasaitiene, D. [5 ]
Cooper, S. [6 ,7 ]
Chi, C. -C. [8 ,9 ]
Kreuter, A. [10 ]
Rall, K. K. [11 ,12 ]
Aberer, W. [13 ]
Riechardt, S. [14 ]
Casabona, F. [15 ]
Powell, J. [16 ]
Brackenbury, F. [17 ]
Erdmann, R. [18 ]
Lazzeri, M. [19 ]
Barbagli, G. [19 ]
Wojnarowska, F. [20 ]
机构
[1] Univ Nottingham, Ctr Evidence Based Dermatol, Nottingham NG7 2RD, England
[2] Univ Tubingen, Inst Gen Practice & Interprofess Care, Tubingen, Germany
[3] Deutsch Gesell Kinderchirurg, Off Paediat Surg, Bonn, Germany
[4] Cantonal Hosp Lucerne, Deptartment Obstet & Gynecol, Deutsch Gesell Gynakol & Geburtshilfe, Luzern, Switzerland
[5] Republican Hosp Panevezys, Dept Skin & Venereal Dis, Lithuanian Assoc Dermatovenereologists, Panevezys, Lithuania
[6] Oxford Univ Hosp NHS Trust, Dept Dermatol, Oxford, England
[7] Univ Oxford, Oxford, England
[8] Chang Gung Mem Hosp, Dept Dermatol, Chiayi, Taiwan
[9] Chang Gung Univ, Coll Med, Taoyuan, Taiwan
[10] HELIOS St Elisabeth Hosp Oberhausen, Dept Dermatol Venereol & Allergol, Oberhausen, Germany
[11] Univ Tubingen Hosp, Res Ctr, Tubingen, Germany
[12] Univ Tubingen Hosp, Dept Womens Hlth, Tubingen, Germany
[13] Med Univ Graz, Dept Dermatol, Graz, Austria
[14] Univ Hamburg, Dept Urol & Paediat Urol, Deutsch Gesell Urol, Hamburg, Germany
[15] Osped Andrea Gallino, Chirurg Plast Rigenerat, SC Chirurg Plast, Genoa, Italy
[16] Hampshire Hosp Fdn Trust, Dept Dermatol, Winchester, Hants, England
[17] Assoc Lichen Sclerosus & Vulval Hlth, Www Lichensclerosus Org, Oxford, England
[18] Charite, Div Evidence Based Med, Klin Dermatol Venerol & Allergol, Dev Search Strategy & Performance Literature Sear, D-13353 Berlin, Germany
[19] Ctr Chirurg Toscano, Arezzo, Italy
[20] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Clin Med, Oxford OX3 9DU, England
关键词
BALANITIS XEROTICA OBLITERANS; EXTRACELLULAR-MATRIX PROTEIN-1; ET-ATROPHICUS; CLOBETASOL PROPIONATE; FOLLOW-UP; PHOTODYNAMIC THERAPY; BORRELIA-BURGDORFERI; TOPICAL APPLICATION; RISK-FACTORS; PENILE;
D O I
10.1111/jdv.13136
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Lichen sclerosus (LS) is an inflammatory skin disease that usually involves the anogenital area. All patients with symptoms or signs suspicious of lichen sclerosus should be seen at least once initially by a physician with a special interest in the disease in order to avoid delay in diagnosis, as early treatment may cure the disease in some and reduce or prevent scarring. The diagnosis is made clinically in most cases. Biopsies should only be performed under certain circumstances. The gold standard for treatment remains potent to very potent topical steroids; however, mild and moderate disease in boys and men may be cured by circumcision. Certain triggers should be avoided. http://www.euroderm.org/images/stories/guidelines/2014/S3-Guideline-on-Lichen-sclerosus.pdf http://www.awmf.org/fachgesellschaften/mitgliedsgesellschaften/visitenkarte/fg/deutsche-gesellschaft-fuer-gynaekologie-und-geburtshilfe-dggg.html.
引用
收藏
页码:E1 / E43
页数:43
相关论文
共 170 条
[111]   British Association of Dermatologists' guidelines for the management of lichen sclerosus 2010 [J].
Neill, S. M. ;
Lewis, F. M. ;
Tatnall, F. M. ;
Cox, N. H. .
BRITISH JOURNAL OF DERMATOLOGY, 2010, 163 (04) :672-682
[112]  
Novartis, 2010, EL PRESCR INF
[113]   Topical oxatomide: An alternative approach for the treatment of vulvar lichen sclerosus [J].
Origoni, M ;
Ferrari, D ;
Rossi, M ;
Gandini, F ;
Sideri, M ;
Ferrari, A .
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 1996, 55 (03) :259-264
[114]  
Owen Caroline M, 2002, J Obstet Gynaecol, V22, P209
[115]   Autoantibodies to extracellular matrix protein 1 in lichen sclerosus [J].
Oyama, N ;
Chan, I ;
Neill, SM ;
Hamada, T ;
South, AP ;
Wessagowit, V ;
Wojnarowska, F ;
D'Cruz, D ;
Hughes, GJ ;
Black, MM ;
McGrath, JA .
LANCET, 2003, 362 (9378) :118-123
[116]   Treatments for psoriasis and the risk of malignancy [J].
Patel, Rita V. ;
Clark, Lily N. ;
Lebwohl, Mark ;
Weinberg, Jeffrey M. .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2009, 60 (06) :1001-1017
[117]   Circulating Anti-BP180 NC16a and Anti-BP230 Autoantibodies in Patients with Genital Lichen Sclerosus Do Not Correlate with Disease Activity and Pruritus [J].
Patsatsi, Aikaterini ;
Kyriakou, Aikaterini ;
Mantas, Athanasios ;
Vayilis, Dimitrios ;
Patsialas, Christos ;
Sotiriadis, Dimitrios .
ACTA DERMATO-VENEREOLOGICA, 2014, 94 (06) :711-712
[118]   Congenital Phimosis in Patients With and Without Lichen Sclerosus: Distinct Expression Patterns of Tissue Remodeling Associated Genes [J].
Pilatz, Adrian ;
Altinkilic, Bora ;
Schormann, Eileen ;
Maegel, Lavinia ;
Izykowski, Nicole ;
Becker, Jan ;
Weidner, Wolfgang ;
Kreipe, Hans ;
Jonigk, Danny .
JOURNAL OF UROLOGY, 2013, 189 (01) :268-274
[119]   KOEBNER PHENOMENON IN LICHEN-SCLEROSUS-ET-ATROPHICUS [J].
POCK, L .
DERMATOLOGICA, 1990, 181 (01) :76-77
[120]  
Powell J, 2002, J REPROD MED, V47, P706