Evidence-based (S3) Guideline on (anogenital) Lichen sclerosus

被引：196

作者：

Kirtschig, G. ^{[1
,2
]}

Becker, K. ^{[3
]}

Guenthert, A. ^{[4
]}

Jasaitiene, D. ^{[5
]}

Cooper, S. ^{[6
,7
]}

Chi, C. -C. ^{[8
,9
]}

Kreuter, A. ^{[10
]}

Rall, K. K. ^{[11
,12
]}

Aberer, W. ^{[13
]}

Riechardt, S. ^{[14
]}

Casabona, F. ^{[15
]}

Powell, J. ^{[16
]}

Brackenbury, F. ^{[17
]}

Erdmann, R. ^{[18
]}

Lazzeri, M. ^{[19
]}

Barbagli, G. ^{[19
]}

Wojnarowska, F. ^{[20
]}

机构：

[1] Univ Nottingham, Ctr Evidence Based Dermatol, Nottingham NG7 2RD, England

[2] Univ Tubingen, Inst Gen Practice & Interprofess Care, Tubingen, Germany

[3] Deutsch Gesell Kinderchirurg, Off Paediat Surg, Bonn, Germany

[4] Cantonal Hosp Lucerne, Deptartment Obstet & Gynecol, Deutsch Gesell Gynakol & Geburtshilfe, Luzern, Switzerland

[5] Republican Hosp Panevezys, Dept Skin & Venereal Dis, Lithuanian Assoc Dermatovenereologists, Panevezys, Lithuania

[6] Oxford Univ Hosp NHS Trust, Dept Dermatol, Oxford, England

[7] Univ Oxford, Oxford, England

[8] Chang Gung Mem Hosp, Dept Dermatol, Chiayi, Taiwan

[9] Chang Gung Univ, Coll Med, Taoyuan, Taiwan

[10] HELIOS St Elisabeth Hosp Oberhausen, Dept Dermatol Venereol & Allergol, Oberhausen, Germany

[11] Univ Tubingen Hosp, Res Ctr, Tubingen, Germany

[12] Univ Tubingen Hosp, Dept Womens Hlth, Tubingen, Germany

[13] Med Univ Graz, Dept Dermatol, Graz, Austria

[14] Univ Hamburg, Dept Urol & Paediat Urol, Deutsch Gesell Urol, Hamburg, Germany

[15] Osped Andrea Gallino, Chirurg Plast Rigenerat, SC Chirurg Plast, Genoa, Italy

[16] Hampshire Hosp Fdn Trust, Dept Dermatol, Winchester, Hants, England

[17] Assoc Lichen Sclerosus & Vulval Hlth, Www Lichensclerosus Org, Oxford, England

[18] Charite, Div Evidence Based Med, Klin Dermatol Venerol & Allergol, Dev Search Strategy & Performance Literature Sear, D-13353 Berlin, Germany

[19] Ctr Chirurg Toscano, Arezzo, Italy

[20] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Clin Med, Oxford OX3 9DU, England

来源：

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY | 2015年 / 29卷 / 10期

关键词：

BALANITIS XEROTICA OBLITERANS; EXTRACELLULAR-MATRIX PROTEIN-1; ET-ATROPHICUS; CLOBETASOL PROPIONATE; FOLLOW-UP; PHOTODYNAMIC THERAPY; BORRELIA-BURGDORFERI; TOPICAL APPLICATION; RISK-FACTORS; PENILE;

D O I：

10.1111/jdv.13136

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Lichen sclerosus (LS) is an inflammatory skin disease that usually involves the anogenital area. All patients with symptoms or signs suspicious of lichen sclerosus should be seen at least once initially by a physician with a special interest in the disease in order to avoid delay in diagnosis, as early treatment may cure the disease in some and reduce or prevent scarring. The diagnosis is made clinically in most cases. Biopsies should only be performed under certain circumstances. The gold standard for treatment remains potent to very potent topical steroids; however, mild and moderate disease in boys and men may be cured by circumcision. Certain triggers should be avoided. http://www.euroderm.org/images/stories/guidelines/2014/S3-Guideline-on-Lichen-sclerosus.pdf http://www.awmf.org/fachgesellschaften/mitgliedsgesellschaften/visitenkarte/fg/deutsche-gesellschaft-fuer-gynaekologie-und-geburtshilfe-dggg.html.

引用

页码：E1 / E43

页数：43

共 170 条

[1] Development of male genital lichen sclerosus in penile reconstruction skin grafts after cancer surgery: an unreported complication
Abdelbaky, Ather M.
Aluru, Pavan
Keegan, Philip
Greene, Damien R.
[J]. BJU INTERNATIONAL, 2012, 109 (05) : 776 - 779
[2] Peristomal lichen sclerosus: the role of occlusion and urine exposure?
Al-Niaimi, F.
Lyon, C.
[J]. BRITISH JOURNAL OF DERMATOLOGY, 2013, 168 (03) : 643 - 646
[3] AlonsoLlamazares J, 1997, ACTA DERM-VENEREOL, V77, P299
[4] [Anonymous], 1988, BR J DERMATOL
[5] Aslanian Flavia M N P, 2006, J Dtsch Dermatol Ges, V4, P842, DOI 10.1111/j.1610-0387.2006.06087.x
[6] Azurdia RM, 1999, BRIT J DERMATOL, V140, P79
[7] Long-term follow-up of patients with lichen sclerosus: Does it really happen?
Balasubramaniam, P.
Lewis, F. M.
[J]. JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2007, 27 (03) : 282 - 282
[8] The contribution of drugs to lichen sclerosus
Baldo, M.
Ali, I.
Wojnarowska, F.
[J]. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2014, 39 (02) : 234 - 234
[9] Childhood vulval lichen sclerosus: autoimmunity to the basement membrane zone protein BP180 and its relationship to autoimmunity
Baldo, M.
Bhogal, B.
Groves, R. W.
Powell, J.
Wojnarowska, F.
[J]. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2010, 35 (05) : 543 - 545
[10] T cells reactive with the NC16A domain of BP180 are present in vulval lichen sclerosus and lichen planus
Baldo, M.
Bailey, A.
Bhogal, B.
Groves, R. W.
Ogg, G.
Wojnarowska, F.
[J]. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2010, 24 (02) : 186 - 190

← 1 2 3 4 5 6 7 8 9 10 →