Glomerular filtration rate estimation and measurement: The quest for precision

被引:3
作者
Delanaye, Pierre [1 ]
机构
[1] Univ Liege, CHU Sart Tilman CHU ULg, Serv Nephrol Dialyse, B-4000 Liege, Belgium
来源
NEPHROLOGIE & THERAPEUTIQUE | 2018年 / 14卷
关键词
Creatinine; Cystatin C; Glomerular filtration rate; lohexol; GFR ESTIMATING EQUATIONS; CHRONIC KIDNEY-DISEASE; CYSTATIN-C; SERUM CREATININE; CKD-EPI; REFERENCE INTERVALS; PLASMA-CLEARANCE; EXTERNAL VALIDATION; CLINICAL-PRACTICE; RENAL CLEARANCE;
D O I
10.1016/j.nephro.2018.02.005
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Glomerular filtration rate measurement is still the best way to assess the global renal function. In daily practice, glomerular filtration rate is estimated by creatinine-based equations. Serum creatinine as a renal biomarker has however several limitations. We discuss the current recommended creatinine-based equations. The potential added value of a new biomarker, cystatin C, and alternative equations will be discussed. Finally, the potential interest of measured glomerular filtration rate by a reference method in specific patients and/or situations will be discussed and justified. (C) 2018 Societe francophone de nephrologie, dialyse et transplantation. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:S59 / S66
页数:8
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